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Chloride Channel

Chloride Channel

Cat. No. Product Name CAS No. Information
CSN27627 T16Ainh-A01 552309-42-9 T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC).
CSN12365 Shikonin   517-89-5 Shikonin is an inhibitor of TMEM16A chloride channel with IC50 of 6.5 M, its a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc..
CSN15941 Selamectin 220119-17-5 Selamectin is an avermectin derivative prepared by hydrolysis and oximation of doramectin Selamectin is a potent nematocide used for the treatment of parasites which selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission
CSN11822 R(+)-IAA-94 54197-31-8 R-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels
CSN22216 NS1652 1566-81-0 NS1652 is a reversible anion conductance inhibitor blocks chloride channel with an IC50 of 16 M in human and mouse red blood cells
CSN21767 NPPB   107254-86-4 NPPB can act as a blocker of the chloride channel with IC50 of 100 nM-100 M and inhibitor of cyclooxygenase IC50 8 M
CSN12665 Niflumic Acid   4394-00-7 Niflumic acid, a Ca2-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
CSN25684 MONNA 1572936-83-4 MONNA is a blocker of TMEM16A (Anoctamin-1) with IC50 of 80 nM.
CSN19806 IAA-94 53108-00-2 IAA-94 is an indanyloxyacetic acid IAA inhibitor of chloride channels that binds channels in bovine kidney cortex microsomes with a Ki value of 1 M
CSN22401 Fluxametamide 928783-29-3 Fluxametamide is an insecticide with wide spectrum acts as an antagonist of GABA- and glutamate-gated chloride channels with IC50 of 195 nM and 225 nM for M domestica GABACls and GluCls
CSN23818 Fluralaner 864731-61-3 Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
CSN33111 Endovion 265646-85-3 Endovion is a blocker of both VRAC and CaCC with IC50 value around 400nM for blocking swelling-activated anion currents in HEK293 cells.
CSN25670 Ani 9 356102-14-2 Ani 9 is selective TMEM16A blocker with IC50 of 77 nM.
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