Welcome to CSNpharm! For Research Use Only!
Home Compound Arrays Promotion +1-708-781-1677 sales@csnpharm.com    

Chk

Chk

Cat. No. Product Name CAS No. Information
CSN23009 NSC 109555 Ditosylate 66748-43-4 NSC 109555 Ditosylate is a selective, reversible, ATP-competitive Chk2 inhibitor with IC50 of 0.2 μM.
CSN17600 LY2606368 2HCl 1234015-54-3 LY2606368 Prexasertib is a selective Chk1 inhibitor with IC50 value 1nM modest to Chk2 and Rsk with IC50 values of 8nM and 10nM
CSN21202 SB 218078 135897-06-2 Inhibitor of checkpoint kinase 1 Chk1 that displays selectivity over other protein kinases IC50 values are 15 250 and 1000 nM for Chk1 cdc2 and PKC respectively Abrogates G2 cell cycle arrest caused by -irradiation and topoisomerase I inhibition Potentiates cytotoxicity of DNA-damaging drugs enhancing the efficacy of some chemotherapeutics
<< PREV 1 NEXT >>