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CFTR

CFTR

Cat. No. Product Name CAS No. Information
CSN16162 Xipamide   14293-44-8 Xipamide a sulfonamide diuretic drug can block sodium reabsorption in distal tubules of the kidney and the cystic fibrosis transmembrane conductance regulator CFTR chloride channel It is used for the treatment of oedema and hypertension
CSN12266 PTC-124   775304-57-9 PTC-124 is nonsense allele inhibitor used to treat Duchenne muscular dystrophy
CSN16935 PPQ-102 931706-15-9 PPQ-102 is a potent and voltage-independent CFTR inhibitor which completely inhibit CFTR chloride current with IC50 approximately 90 nM
CSN23041 PG 01 853138-65-5 PG 01 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator.
CSN11339 Lubiprostone   136790-76-6 Lubiprostone is an ClC-2 chloride channel activator used in the treatment of idiopathic chronic constipation.
CSN13745 IOWH-032 1191252-49-9 IOWH-032 is a potent CFTR inhibitor IC50101 M in T84 and CHO-CFTR cell based assays
CSN23889 FDL169 1628416-28-3 FDL169 is CFTR inhibitor. It is an experimental therapy for cystic fibrosis (CF). Phase II.
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