Welcome to CSNpharm! For Research Use Only!
Home +1-708-781-1677

CFTR

CFTR

Cat. No. Product Name CAS No. Information
CSN12300 VX-809   936727-05-8 VX-809 acts to correct CFTR mutations common in cystic fibrosis by increasing mutant CFTR (F508del-CFTR) maturation with an EC50 of 0.1 M.
CSN15718 VX-661 1152311-62-0 VX-661 is a F508del CFTR corrector and is believed to help CFTR protein reach the cell surface
CSN12266 PTC-124   775304-57-9 PTC-124 is nonsense allele inhibitor used to treat Duchenne muscular dystrophy
CSN16935 PPQ-102 931706-15-9 PPQ-102 is a potent and voltage-independent CFTR inhibitor which completely inhibit CFTR chloride current with IC50 approximately 90 nM
CSN11339 Lubiprostone 136790-76-6 Lubiprostone is an ClC-2 chloride channel activator used in the treatment of idiopathic chronic constipation.
CSN18426 KM11060   774549-97-2 KM11060 corrects the F508del-CFTR trafficking defect also shows inhibition on PDE5 activity
CSN13698 Ivacaftor   873054-44-5 Ivacaftor is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM respectively
CSN17491 Ivacaftor Hydrate 1134822-07-3 Ivacaftor is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM respectively
CSN17492 Ivacaftor Benzenesulfonate 1134822-09-5 Ivacaftor benzenesulfonate is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM respectively
CSN13745 IOWH-032 1191252-49-9 IOWH-032 is a potent CFTR inhibitor IC50101 M in T84 and CHO-CFTR cell based assays
CSN18214 GlyH-101 328541-79-3 GlyH-101 a glycinyl hydrazone compound is a reversible and voltage-dependent CFTR chloride channel blocker with Ki of 43 M
CSN21065 GLPG1837   1654725-02-6 GLPG-1837 is a cystic fibrosis transmembrane conductance regulator CFTR potentiator1 shows enhanced efficacy on CFTR mutants harboring Class III mutations compared to Ivacaftor
CSN19349 CFTR(inh)-172 307510-92-5 CFTR inh-172 is an reversibly inhibitor of CFTR short-circuit current in less than 2 minutes in a voltage-independent manner with Ki 300 nM
CSN22372 CFTR Corrector 1897384-89-2 CFTR corrector is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator extracted from patent US9782408.
CSN23041 PG 01 853138-65-5
<< PREV 1 NEXT >>