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CDK

CDK

Cat. No. Product Name CAS No. Information
CSN16440 Wogonin   632-85-9 Wogonin acts as an inhibitor of COX2 with IC50 of 46 M without affecting COX-1 and inhibits the NF-B pathway-mediated iNOs induction. Wogonin can be isolated from the root of scutellaria baicalensis georgi.
CSN23869 Senexin B 1449228-40-3 Senexin B is a potent and selective CDK8/19 inhibitor.
CSN11862 Roscovitine   186692-46-6 Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM and shows little effect on CDK4/6.
CSN11862 Roscovitine   186692-46-6 Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM and shows little effect on CDK4/6.
CSN25543 PNU 112455A 21886-12-4 PNU112455A HCl is an ATP site competetive inhibitor of CDK2 and CDK5. The Km for binding to the ATP site of CDK2 and CDK5 is 3.6 and 3.3 mM, respectively.
CSN25261 NSC-95397 93718-83-3 NSC 95397 is irreversible Cdc25 dual specificity phosphatase inhibitor with Ki values of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively.
CSN11014 Flavopiridol 146426-40-6 Flavopiridol is a pan CDK inhibitor with IC50 values of 30nM, 40nM, 20-40nM, 60nM, 875nM and 20nM for CDK1, 2, 4, 6, 7, 9, respectively
CSN11015 Flavopiridol HCl 131740-09-5 Flavopiridol HCl competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM.
CSN18431 Dinaciclib   779353-01-4 Dinaciclib is a potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively.
CSN10712 Cucurbitacin E 18444-66-1 Cucurbitacin E is a widely available plant-derived natural product, making it a useful tool to study actin dynamics in cells and actin-based processes such as cytokinesis.
CSN26129 CDK2 inhibitor 73 2079895-42-2 CDK2 inhibitor 73 is a selective CDK2 inhibitor with IC50 value of 44nM.
CSN22673 Alsterpaullone 237430-03-4 Alsterpaullone is a potent CDK1 and 2 inhibitor with IC50s of 0.035 and 0.08 μM, respectively. It also inhibits GSK-3β and Lck with IC50s of 0.11 and 0.47 μM, respectively.
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