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CDK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN16440 | Wogonin | 632-85-9 | Wogonin acts as an inhibitor of COX2 with IC50 of 46 M without affecting COX-1 and inhibits the NF-B pathway-mediated iNOs induction. Wogonin can be isolated from the root of scutellaria baicalensis georgi. |
| CSN23869 | Senexin B | 1449228-40-3 | Senexin B is a potent and selective CDK8/19 inhibitor. |
| CSN11862 | Roscovitine | 186692-46-6 | Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM and shows little effect on CDK4/6. |
| CSN11862 | Roscovitine | 186692-46-6 | Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM and shows little effect on CDK4/6. |
| CSN25543 | PNU 112455A | 21886-12-4 | PNU112455A HCl is an ATP site competetive inhibitor of CDK2 and CDK5. The Km for binding to the ATP site of CDK2 and CDK5 is 3.6 and 3.3 mM, respectively. |
| CSN25261 | NSC-95397 | 93718-83-3 | NSC 95397 is irreversible Cdc25 dual specificity phosphatase inhibitor with Ki values of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively. |
| CSN11014 | Flavopiridol | 146426-40-6 | Flavopiridol is a pan CDK inhibitor with IC50 values of 30nM, 40nM, 20-40nM, 60nM, 875nM and 20nM for CDK1, 2, 4, 6, 7, 9, respectively |
| CSN11015 | Flavopiridol HCl | 131740-09-5 | Flavopiridol HCl competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. |
| CSN18431 | Dinaciclib | 779353-01-4 | Dinaciclib is a potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively. |
| CSN10712 | Cucurbitacin E | 18444-66-1 | Cucurbitacin E is a widely available plant-derived natural product, making it a useful tool to study actin dynamics in cells and actin-based processes such as cytokinesis. |
| CSN26129 | CDK2 inhibitor 73 | 2079895-42-2 | CDK2 inhibitor 73 is a selective CDK2 inhibitor with IC50 value of 44nM. |
| CSN22673 | Alsterpaullone | 237430-03-4 | Alsterpaullone is a potent CDK1 and 2 inhibitor with IC50s of 0.035 and 0.08 μM, respectively. It also inhibits GSK-3β and Lck with IC50s of 0.11 and 0.47 μM, respectively. |
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