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Cat. No.	Product Name	CAS No.	Information
CSN16440	Wogonin	632-85-9	Wogonin acts as an inhibitor of COX2 with IC50 of 46 M without affecting COX-1 and inhibits the NF-B pathway-mediated iNOs induction. Wogonin can be isolated from the root of scutellaria baicalensis georgi.
CSN24147	Voruciclib	1000023-04-0	Voruciclib is a protein kinase inhibitor specific for the cyclin-dependent kinase 4 (CDK4) with potential antineoplastic activity.
CSN25265	Trilaciclib	1374743-00-6	Trilaciclib is an inhibitor of CDK4 and CDK6 with IC50s of 1 nM and 4 nM, respectively.
CSN22094	Trilaciclib HCl	1977495-97-8	Trilaciclib hydrochloride is a CDK4/6 inhibitor with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively.
CSN24801	TP353	1253799-29-9	TP353 is a CDK7 inhibitor.
CSN24290	THZ532	1702809-22-0	THZ532 is an inactive enantiomer of THZ531.
CSN16220	THZ1	1604810-83-4	THZ1 is a selective and potent covalent CDK7 inhibitor with IC50 binding affinity of 32 nM and inhibits Jurkat cells proliferation with IC50 of 50 nM
CSN22287	THAL-SNS-032	2139287-33-3	THAL-SNS-032 is a selective PROTAC, consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN), targeting on CDK9.
CSN16121	TG-003	719277-26-6	TG003 is a potent inhibitor of Clk1Sty and Clk4 with IC50 of 15-20 nM less potency on Clk2 IC50 200 nM
CSN25349	SR-4853	2387704-62-1	SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 with IC50 of 99 nM, Kd of 98 nM for CDK12 and Kd of 4.9 nM for CDK13. It acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer (TNBC) cell death.
CSN12378	SNS-032	345627-80-7	SNS-032 is a potent inhibitor of cyclin-dependent kinases (CDKs)9, 2 and 7 (IC50 values are 4, 38 and 62 nM respectively).
CSN23869	Senexin B	1449228-40-3	Senexin B is a potent and selective CDK8/19 inhibitor.
CSN23674	SEL120-34A HCl	1609452-30-3	SEL120-34A HCl is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity.
CSN11862	Roscovitine	186692-46-6	Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM and shows little effect on CDK4/6.
CSN19761	Roniciclib	1223498-69-8	Roniciclib is an orally bioavailable cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity, selectively binds to and inhibits the activity of CDK1/Cyclin B, CDK2/Cyclin E, CDK4/Cyclin D1, and CDK9/Cyclin T1, serine/threonine kinases that play key roles in the regulation of the cell cycle progression and cellular proliferation.
CSN16126	R547	741713-40-6	R547 is a potent ATP-competitive inhibitor of CDK124 with Ki of 2 nM3 nM1 nM
CSN22310	CDK9-PROTAC	2118356-96-8	PROTAC CDK9 Degrader-1 is a CRBN-recruiting PROTAC selectively targeting on CDK9, consist of a CDK9 ligand (aminopyrazole analog) linked to a CRBN E3 ligand thalidomide.
CSN25543	PNU 112455A	21886-12-4	PNU112455A HCl is an ATP site competetive inhibitor of CDK2 and CDK5. The Km for binding to the ATP site of CDK2 and CDK5 is 3.6 and 3.3 mM, respectively.
CSN16230	PHA-767491	845714-00-3	PHA-767491 is a potent ATP-competitive dual Cdc7Cdk9 inhibitor with IC50 values of 1034 nM and also an inhibitor of NRF2
CSN24146	PF-06873600	2185857-97-8	PF-06873600 is a selective and orally bioavailable inhibitor of cyclin-dependent kinase (CDK) with Ki of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6 respectively. PF-06873600 has potential antineoplastic activity.
CSN12418	Palbociclib	571190-30-2	Palbociclib is a highly specific inhibitor of Cdk4 and Cdk6 with IC50s of 11 nM and16 nM
CSN18553	NVP-LCQ195	902156-99-4	NVP-LCQ195 is a small molecule heterocyclic inhibitor of CDK1, CDK2, CDK3 and CDK5 with IC50 of 1-42 nM.
CSN25261	NSC-95397	93718-83-3	NSC 95397 is irreversible Cdc25 dual specificity phosphatase inhibitor with Ki values of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively.
CSN16279	NG 52	212779-48-1	NG 52 is a potent cell-permeable reversible selective and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p IC50 7 M and the related Pho85p kinase IC50 2 M
CSN23650	ML 315	1440251-53-5	ML 315 is inhibitor of Clk and DYRK kinases with IC50s of 68, 68 and 231 nM for Clk1, Clk4 and Clk2, 282 and 1156 nM for Dyrk1A and Dyrk1B.
CSN23665	ML 315 HCl	2172559-91-8	ML 315 HCl is inhibitor of Clk and DYRK kinases with IC50s of 68, 68 and 231 nM for Clk1, Clk4 and Clk2, 282 and 1156 nM for Dyrk1A and Dyrk1B.
CSN24194	MC180295	2237942-08-2	MC180295 is a selective CDK9 inhibitor with IC50 values of 5nM, 112nM, 138nM, 159nM, 186nM, 233nM, 367nM, 399nM, 555nM and 712nM for CDK9-Cyclin T1, CDK4-Cyclin D, CDK1-Cyclin B, cdk5-p35, cdk5-p25, cdk2-cyclin A, cdk2-cyclin E, CDK3-Cyclin E, CDK7-CycH/MAT1 and cdk6-cyclin D3.
CSN17760	LEE011 Succinate Hydrate	1374639-79-8	LEE011 succinate is an orally available cyclin-dependent kinase CDK inhibitor targeting cyclin D1CDK4 and cyclin D3CDK6 cell cycle pathway with potential antineoplastic activity
CSN22284	JH-XI-10-02	2209085-22-1	JH-XI-10-02 is a PROTAC selectively targeting on CDK8 with IC50 value of 159nM, and is consist of a warhead target on CDK8 (a Cortistatin A derivate) linked to CRBN ligand Pomalidomide.
CSN11014	Flavopiridol	146426-40-6	Flavopiridol is a pan CDK inhibitor with IC50 values of 30nM, 40nM, 20-40nM, 60nM, 875nM and 20nM for CDK1, 2, 4, 6, 7, 9, respectively
CSN11015	Flavopiridol HCl	131740-09-5	Flavopiridol HCl competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM.
CSN24779	EHT 5372	1425945-60-3	EHT 5372 is a strong inhibitor of DYRK’s family kinases, with IC50s of 0.22, 0.28 nM for DYRK1A and DYRK1B, respectively.
CSN18431	Dinaciclib	779353-01-4	Dinaciclib is a potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively.
CSN16417	CVT-313	199986-75-9	CVT-313 is a potent selective ATP-competitive and reversible inhibitor of CDK2 with IC50 of 05 M for Cdk2A and Cdk2E 42 M for Cdk1B 215 M for Cdk4D1
CSN10712	Cucurbitacin E	18444-66-1	Cucurbitacin E is a widely available plant-derived natural product, making it a useful tool to study actin dynamics in cells and actin-based processes such as cytokinesis.
CSN22367	CDK8-IN-3	1884500-15-5	CDK8-IN-3 is an inhibitor of CDK8 extracted from patent WO2016041618A1, compound example 1.7.
CSN23778	cc671	1618658-88-0	CC-671 is a selective inhibitor of TTK (Mps1) and CLK2 with IC50s of 5 nM and 3 nM, respectively.
CSN17795	Ca2+ Channel Agonist 1	1402821-24-2	Ca2 channel agonist 1 is a N-type Ca2 channel activity agonist with EC50 of 1423 M also inhibits cdk2 kinase activity with EC50 of 334 M
CSN23969	BSJ-03-123	2361493-16-3	BSJ-03-123 is a PROTAC selectively targeting on CDK6, consist of a warhead palbociclib (a CDK inhibitor) linked to a CRBN ligand pomalidomide.
CSN25245	BS-194	1092443-55-4	BS-194 is a selective and potent CDK inhibitor with IC50 values of 3, 30, 30, 250, and 90nM for CDK2, CDK1, CDK5, CDK7, and CDK9, respectively.
CSN20540	BRD6989	642008-81-9	BRD6989 selectively upregulates IL-10 through inhibiting CDK8 activity.
CSN24819	Bohemine	189232-42-6	Bohemine is a potent and selective, cell-permeable, cyclin-dependent kinase (CDK) inhibitor with IC50 = 1 µM. Bohemine is structurally similar to Olomoucine and Roscovitine.
CSN25300	BI-1347	2163056-91-3	BI-1347 is a potent CDK8 inhibitor with an IC50 of 1.1 nM.
CSN21503	AZD5438	602306-29-6	AZD5438 is a potent inhibitor of CDK129 with IC50 of 16620 nM
CSN24735	AZD4573	2057509-72-3	AZD4573 is a potent and selective CDK9 inhibitor with with nanomolar.
CSN21194	Atuveciclib Racemate	1414943-88-6	Atuveciclib Racemate is the racemate form of Atuveciclib.
CSN25869	Atuveciclib	1414943-94-4	Atuveciclib is an orally available and selective PTEFb/CDK9 inhibitor for the treatment of cancer.
CSN13886	LY2835219	1231930-82-7	Abemaciclib Methanesulfonate is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM respectively, used for the treatment of advanced or metastatic breast cancers.
CSN15805	Abemaciclib	1231929-97-7	Abemaciclib is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM respectively, used for the treatment of advanced or metastatic breast cancers.

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