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Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.


Cat. No. Product Name CAS No. Information
CSN27190 CD80-IN-3 486449-65-4 CD80-IN-3 binds with high specificity and low nanomolar affinity to CD80. It has relatively slow off-rates, blocks both CD28 and CTLA-4 binding and inhibits proinflammatory cytokine release in T cell assays with submicromolar potency.
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