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CCR
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN12197 | Vicriviroc Maleate | 599179-03-0 | Vicriviroc maleate is a CCR5 antagonist with IC50 of 0.91 nM in clinical development for the treatment of HIV-1. |
| CSN16904 | TAK-220 | 333994-00-6 | TAK-220 is an orally bioavailable small-molecule CCR5 antagonist |
| CSN22613 | SB297006 | 58816-69-6 | SB297006 is a selective antagonist of CCR3 with IC50 of 39 nM |
| CSN12845 | RS-504393 | 300816-15-3 | RS 504393 is a selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and 100 M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). |
| CSN23164 | Teijin Compound 1 | 1313730-14-1 | Potent CCR2b antagonist |
| CSN17712 | PF-4136309 | 1341224-83-6 | PF-4136309 is a potent, Selective, and orally bioavailable CCR2 antagonist. |
| CSN17807 | NSC 5844 | 140926-75-6 | NSC 5844 is a bisquinoline compound with C-C chemokine receptor type 1 CCR1-agonistic properties |
| CSN11361 | Maraviroc | 376348-65-1 | Maraviroc is a selective CCR5 antagonist (IC50 6.4 nM) and displays potent anti-HIV-1 activity. |
| CSN17640 | INCB3344 | 1262238-11-8 | INCB3344 is a potent and selective small molecule antagonist of the mouse CCR2 receptor and inhibits the binding of CCL2 to mouse monocytes with nanomolar potency (IC50 10 nM). |
| CSN23233 | DAPTA | 106362-34-9 | DAPTA is a potent and selective CCR5 antagonist |
| CSN22175 | CCR5 Antagonist 1 | 716354-86-8 | CCR5 antagonist 1 is a CCR5 antagonist which can inhibit HIV replication extracted from WO 2004054974 A2 |
| CSN18114 | BX471 | 217645-70-0 | BX471 is a potent, selective non-peptide CCR1 antagonist (Ki 1 nM for human CCR1) and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. |
| CSN18182 | BX471 HCl | 288262-96-4 | BX471 HCl is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1) and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. |
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