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CCR

CCR

Cat. No. Product Name CAS No. Information
CSN12197 Vicriviroc Maleate 599179-03-0 Vicriviroc maleate is a CCR5 antagonist with IC50 of 0.91 nM in clinical development for the treatment of HIV-1.
CSN18397 Vercirnon 698394-73-9 Vercirnon is a highly potent antagonist of CCR9, which has been implicated in the aetiology of inflammatory bowel diseases such as Crohns disease.
CSN16904 TAK-220 333994-00-6 TAK-220 is an orally bioavailable small-molecule CCR5 antagonist
CSN22613 SB297006   58816-69-6 SB297006 is a selective antagonist of CCR3 with IC50 of 39 nM
CSN18192 RS-102895 300815-41-2 RS102895 is a potent and specific CCR2 antagonist with binding IC50 of 360 nM, no significant inhibition on CCR1 (IC50 17 M).
CSN13797 RS-102895 HCl 1173022-16-6 RS102895 hydrochloride is a potent and specific CCR2 antagonist with binding IC50 of 360 nM, no significant inhibition on CCR1 (IC50 17 M).
CSN12845 RS-504393 300816-15-3 RS 504393 is a selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and 100 M for inhibition of human recombinant CCR2b and CCR1 receptors respectively).
CSN17712 PF-4136309 1341224-83-6 PF-4136309 is a potent, Selective, and orally bioavailable CCR2 antagonist.
CSN17807 NSC 5844 140926-75-6 NSC 5844 is a bisquinoline compound with C-C chemokine receptor type 1 CCR1-agonistic properties
CSN18995 MK-0812 Succinate 851916-42-2 MK-0812 succinate is a potent and selective CCR2 antagonist with low nM affinity for CCR2 on human monocytes
CSN13664 MK-0812 624733-88-6 MK-0812 is a potent and selective CCR2 antagonist with low nM affinity for CCR2 on human monocytes.
CSN11361 Maraviroc 376348-65-1 Maraviroc is a selective CCR5 antagonist (IC50 6.4 nM) and displays potent anti-HIV-1 activity.
CSN17640 INCB3344 1262238-11-8 INCB3344 is a potent and selective small molecule antagonist of the mouse CCR2 receptor and inhibits the binding of CCL2 to mouse monocytes with nanomolar potency (IC50 10 nM).
CSN13799 INCB 3284 Dimesylate 887401-93-6 INCB 3284 is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM.
CSN18528 INCB 3284 887401-92-5 INCB 3284 is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM (inhibition of monocyte chemoattractant protein-1 binding to hCCR2).
CSN22186 GW 766994 408303-43-5 GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist, which has entered clinical trial for asthma and eosinophilic bronchitis.
CSN22234 GSK2239633A 1240516-71-5 GSK2239633A is a CC-chemokine receptor 4 CCR4 antagonist which inhibits the binding of 125I-TARC to human CCR4 with a pIC50 of 796011
CSN23233 DAPTA   106362-34-9 DAPTA is a potent and selective CCR5 antagonist
CSN15987 Cenicriviroc 497223-25-3 Cenicriviroc is an oral, dual CCR2CCR5 antagonist, and displays potent anti-inflammatory and aninfective activity.
CSN22175 CCR5 Antagonist 1 716354-86-8 CCR5 antagonist 1 is a CCR5 antagonist which can inhibit HIV replication extracted from WO 2004054974 A2
CSN18114 BX471 217645-70-0 BX471 is a potent, selective non-peptide CCR1 antagonist (Ki 1 nM for human CCR1) and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
CSN18182 BX471 HCl 288262-96-4 BX471 hydrochloride is a potent, selective non-peptide CCR1 antagonist (Ki 1 nM for human CCR1) and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
CSN20665 AZD-2098 566203-88-1 AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor, used for asthma research.
CSN20666 AZD-1678 942137-41-9 AZD1678 is a potent CC-chemokine receptor 4 (CCR4) inhibitor, used for asthma research.
CSN22732 C 021 2HCl 864289-85-0
CSN22729 BX 513 HCl 1216540-18-9
CSN22720 BMS CCR2 22 445479-97-0
CSN23102 SB 328437 247580-43-4
CSN23164 Teijin Compound 1 1313730-14-1
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