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Cathepsin

Cathepsin

Cat. No. Product Name CAS No. Information
CSN17677 VBY-825 1310340-58-9 VBY-825 is a reversible cathepsin inhibitor with high potency against cathepsins B L S and V
CSN13484 Odanacatib   603139-19-1 Odanacatib is a potent selective and neutral inhibitor of cathepsin K humanrabbit with IC50 of 02 nM1 nM and demonstrated high selectivity versus off-target cathepsin B L S
CSN22465 MIV-247 1352817-76-5 MIV-247 is a selective cathepsin S inhibitor with Kis of 21 42 and 75 nM for human mouse and cynomolgus monkey cathepsin S respectively
CSN10529 MG-101 110044-82-1 MG-101 is a potent inhibitor of cysteine proteases including calpain I (Ki 190 nM), calpain II (Ki 220 nM), cathepsin B (Ki 150 nM), and cathepsin L (Ki 500 pM).
CSN20392 MDL28170 88191-84-8 MDL28170 is a potent selective inhibitor of calpain and cathepsin B Ki values are 10 and 25 nM respectively that does not inhibit trypsin-like serine proteases MDL28170 rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo
CSN17758 LY3000328 1373215-15-6 LY 3000328 is a highly selective and potent Cathepsin S inhibitor with IC50 of 7.75.85 nM and 1.671.17 nM for hCat S and mCat S respectively, can be used in treatment for abdominal aortic aneurysm.
CSN17411 Leupeptin Hemisulfate 103476-89-7 Leupeptin Hemisulfate is a reversible serinecysteine protease inhibitor inhibits cathepsins B H L and S calpain and trypsin
CSN13069 Furan-2-Carboxylic Acid   88-14-2 Furan-2-carboxylic acid, a natural product isolated and purified from the herbs of Hexagonia speciosa with anti-bacterial effect, is also an orally active selective human cathepsin K inhibitor which may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosis.
CSN16115 CA-074 Methyl Ester 147859-80-1 CA-074 Methyl Ester is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor.
CSN16928 Balicatib 354813-19-7 Balicatib is a potent and selective inhibitor of cathepsin K with 10-100 fold more potent in cell-based enzyme occupancy assays than against cathepsin B L and S
CSN22577 5,5-Dimethyl-2,4-oxazolidinedione   695-53-4 5,5-Dimethyl-2,4-oxazolidinedione is a cathepsin K inhibitor, its an anticonvulsant.
CSN14152 1-Hydroxyrutaecarpine 53600-24-1
CSN22735 CA 074 134448-10-5
CSN22995 Calpain Inhibitor II 145757-50-2
CSN22874 L 006235 294623-49-7
CSN23117 SID 26681509 958772-66-2
CSN20340 ONO-5334 868273-90-9
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