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CaSR
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN26427 | Tecalcet Hydrochloride | 177172-49-5 | Tecalcet Hydrochloride, an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride increases the sensitivity to activation by extracellular Ca2+. |
| CSN11988 | Strontium Ranelate | 135459-87-9 | Strontium ranelate stimulates the calcium sensing receptors (CaSR) and leads to the differentiation of pre-osteoblast to osteoblast which increases the bone formation. |
| CSN24273 | SB-423562 | 351490-27-2 | SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist. |
| CSN11585 | NPS-2143 | 284035-33-2 | NPS-2143 is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2 concentrations and parathyroid hormone secretion, respectively. |
| CSN18211 | NPS-2143 hydrochloride | 324523-20-8 | NPS-2143 HCl is a potent and selective calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively. |
| CSN26428 | Ligustroflavone | 260413-62-5 | Ligustroflavone, extracted from Ligustrum lucidum, is a potential candidate as calcium-sensing receptor (CaSR) antagonist. Ligustroflavone exhibits protective effects against diabetic osteoporosis in mice[1]. |
| CSN20404 | Etelcalcetide hydrochloride | 1334237-71-6 | Etelcalcetide HCl is the HCl salt of etelcalcetide is a calcium-sensing receptor agonist for the treatment of secondary hyperparathyroidism for patients with chronic kidney disease (CKD) on hemodialysis. |
| CSN12305 | Cinacalcet | 226256-56-0 | Cinacalcet is an orally active second-generation calcimimetic compound and represents a class of compounds for the treatment of hyperparathyroidism |
| CSN12758 | Cinacalcet hydrochloride | 364782-34-3 | Cinacalcet HCl is an orally active calcimimetic compound and represents a class of compounds for the treatment of hyperparathyroidism. |
| CSN18295 | Calcium-Sensing Receptor Antagonists I | 478963-79-0 | Calcium-sensing receptor antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors |
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