CaMK
Cat. No. | Product Name | CAS No. | Information |
---|---|---|---|
CSN26523 | Verosudil | 1414854-42-4 | Verosudil, also known as AR-12286, is a potent and selective Rho kinase inhibitor. AR-12286 was well tolerated and provided statistically significant reduction in IOP (intraocular pressure) in patients with XFS (exfoliation syndrome) and OHT (ocular hypertension) or XFG (exfoliative glaucoma). This drug may represent an additional therapeutic paradigm for the treatment of XFG. |
CSN19242 | STO-609 | 52029-86-4 | STO-609 is a specific inhibitor of the Ca2Calmodulin-dependent protein kinase kinase CaM-KK that inhibits the activities of recombinant CaM-KK and CaM-KK isoforms with Ki values of 80 and 15 ngmL respectively and also inhibits their autophosphorylation activities |
CSN20500 | STO-609 acetate | 1173022-21-3 | STO-609 acetate is a cell-permeable inhibitor of calciumcalmodulin-dependent kinase kinases CaMKK isoforms CaMKK and CaMKK Ki 80 and 15 ngmL respectively |
CSN20312 | Rimacalib | 215174-50-8 | SMP-114 is a CaMKII inhibitor with oral bioavailability and mediates the reduction SR Ca(2) leak and arrhythmogenic cellular correlates. |
CSN16664 | NH125 | 278603-08-0 | NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM also a potent histidine kinase inhibitor |
CSN18794 | KN-93 Phosphate | 1188890-41-6 | KN-93 Phosphate a potent Ca2calmodulin-dependent protein kinase II CaMKII selective inhibitor with Ki of 370 nM is the water soluble version of KN-93 |
CSN19063 | KN-93 phosphate | 1913269-12-1 | KN-93 is a selective inhibitor of Ca2calmodulin-dependent kinase II CaMKII competitively blocking CaM binding to the kinase Ki 370 nM |
CSN11255 | KN-93 | 139298-40-1 | KN-93 is a potent Ca2calmodulin-dependent protein kinase II CaMKII selective inhibitor with Ki of 370 nM |
CSN16900 | KN-93 hydrochloride | 1956426-56-4 | KN-93 HCl is a membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM. |
CSN16913 | KN-92 phosphate | 1135280-28-2 | KN-92 phosphate is an inactive derivative of KN-93 KN-93 is a selective inhibitor of Ca2calmodulin-dependent kinase II CaMKII competitively blocking CaM binding to the kinase Ki 370 nM |
CSN19064 | KN-92 | 176708-42-2 | KN-92 is an inactive derivative of KN-93 KN-93 is a selective inhibitor of Ca2calmodulin-dependent kinase II CaMKII competitively blocking CaM binding to the kinase Ki 370 nM |
CSN17850 | KN-92 hydrochloride | 1431698-47-3 | KN-92 HCl a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). |
CSN24178 | Cabamiquine | 1469439-69-7 | DDD107498 is a multiple-stage antimalarial agent targeting on eEF2. |
CSN22017 | CV-159 | 86384-98-7 | CV-159 is a unique dihydropyridine Ca2+ antagonist with an anti-calmodulin (CaM) action and shows antiinflammatory activities. |
CSN22547 | CRT0066101 dihydrochloride | 1883545-60-5 | CRT0066101 reduces BrdU incorporation, increases apoptosis, blocks neurotensin (NT)-induced PKD1/2 activation, reduces NT-induced PKD-mediated Hsp27 phosphorylation, attenuates PKD1-mediated NF-κB activation, and abrogates expression of NF-κB-dependent-dependent proliferative and pro-survival proteins. |
CSN17563 | CaMKII-IN-1 | 1208123-85-6 | CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM, displaying significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC. |
CSN23191 | N-(6-Aminohexyl)naphthalene-1-sulfonamide hydrochloride | 61714-25-8 | Calmodulin antagonist |
CSN23190 | W-13 HCl | 88519-57-7 | Calmodulin antagonist |
CSN23192 | W-7 isomer hydrochloride | 69762-85-2 | Calmodulin antagonist |
CSN22737 | Calmidazolium chloride | 57265-65-3 | Calmidazolium Chloride is a calmodulin antagonist. |
CSN22694 | Autocamtide-2-related inhibitory peptide, myristoylated | 201422-04-0 | Autocamtide-2-related Inhibitory Peptide, myristoylated is a CaM kinase II inhibitor that enhances cell permeable derivative of Autocamtide-2-related inhibitory peptide. |
CSN22693 | Autocamtide-2-related inhibitory peptide | 167114-91-2 | Autocamtide-2-related Inhibitory Peptide is a selective and potent calmodulin-dependent protein kinase II (CaM kinase II) inhibitor with IC50 of 40 nM. |
CSN22660 | A-7 HCl | 79127-24-5 | A-7 HCl is a potent calmodulin antagonist. |
CSN22750 | Zaldaride maleate | 109826-27-9 |