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Calcium Channel

Calcium Channel

Cat. No. Product Name CAS No. Information
CSN18679 Zonisamide   68291-97-4 Zonisamide, a 1,2 benzisoxazole derivative, is developed as an antiepileptic drug.
CSN18390 Zonisamide sodium 68291-98-5 Zonisamide sodium is a 1,2 benzisoxazole derivative and the first agent of this chemical class to be developed as an antiepileptic drug.
CSN25647 Verapamil 52-53-9 Verapamil is a phenylalkylamine class L-type calcium channel blocker. It may be a potential Covid-19 drug.
CSN27384 Urolithin C 165393-06-6 Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation.
CSN16638 Taurine   107-35-7 Taurine is a widely distributed organic compound in animal tissues which possesses function of conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization, and modulation of calcium signaling.
CSN22176 18:0 LYSO-PE 69747-55-3 Stearoyl lysophosphatidylethanolamine is an agent that can induce Ca2i increase.
CSN24655 SAK3 1256269-87-0 SAK 3 is a effective activator of CaV3.1 and CaV3.3.
CSN20495 S107 927871-76-9 S107 is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant andor PKA-phosphorylated channels.
CSN24653 Ryanodine 15662-33-6 Ryanodine is an inhibitor of Ca2+ release from sarcoplasmic reticulum with IC50 values of 10 and 2.8 nM in skeletal and cardiac muscle respectively.
CSN13104 Ranolazine   95635-55-5 Ranolazine inhibits calcium uptake via the sodiumcalcium channel, is used to treat chronic angina.
CSN12787 Ranolazine dihydrochloride 95635-56-6 Ranolazine 2HCl is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.
CSN29534 Pranidipine 99522-79-9 Pranidipine is an effective, long-acting 1,4-dihydropyridine calcium channel blocker. It also has antihypertensive activity.
CSN27750 NS-638 150493-34-8 NS-638 is nonpeptide Ca2+-channel blocker with IC50 value of 3.4μM for blocking K+-stimulated intracellular Ca2+-elevation.
CSN11560 Nilvadipine 75530-68-6 Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM.
CSN11555 Nifedipine   21829-25-4 Nifedipine is a dihydropyridine calcium channel blocker used to lower hypertension and to treat angina
CSN11401 Nicardipine hydrochloride   54527-84-3 Nicardipine HCl is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.
CSN16159 Neomycin sulfate   28002-70-2 Neomycin Trisulfate Salt is an aminoglycoside antibiotic and calcium channel protein inhibitor.
CSN11406 Methyl 3,4,5-Trimethoxycinnamate 7560-49-8 Methyl 3,4,5-trimethoxycinnamate, a natural product isolated and purified from the herbs of Alstonia yunnanensis, may protect the heart from arrhythmias via its inhibitory effect on calcium channel.
CSN27383 Levamlodipine   103129-82-4 Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina.
CSN21704 Lemildipine 94739-29-4 Lemildipine is a 1,4-dihydropyridine calcium channel blocker which has potential to treat hypertension and cerebrovascular ischemia.
CSN12998 Lamotrigine   84057-84-1 Lamotrigine is a member of the sodium channel blocking class of antiepileptic drugs which can block L-, N-, and P-type calcium channels and has weak 5-HT3 receptor inhibition.
CSN11261 Lacidipine   103890-78-4 Lacidipine is a L-type calcium channel blocker, used for treating high blood pressure.
CSN21683 Iganidipine 119687-33-1 Iganidipine is a blocker of calcium channel that used for the treatment of glaucoma. 
CSN16274 Fraxinellone 28808-62-0 Fraxinellone, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz. with neuroprotective, vasorelaxing, insecticidal, and antimicrobial activities, is a selective blocker of voltage-dependent Ca2 channel, while dictamine relaxed the rat aorta by suppressing the Ca2 influx through both voltage-dependent and receptor-operated Ca2 channels, and can dramatically induce apoptosis of activated peripheral CD4() T cells in vivo, consequently resulting in less CD4() T-cell activation and infiltration to the liver.
CSN17326 Felodipine   72509-76-3 Felodipine is a long-acting 14-dihydropyridine calcium channel blocker
CSN10948 Ethosuximide   77-67-8 Ethosuximide is used to treat absence seizures.
CSN16302 Efonidipine 111011-63-3 Efonidipine is a dual T-type and L-type calcium channel blocker (CCB).
CSN21615 Dopropidil 79700-61-1 Dopropidil is a modulator of intracellular calcium with antagonist activity and anti-anginal effects.
CSN10823 Diltiazem hydrochloride   33286-22-5 Diltiazem HCl is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.
CSN20804 DHBP dibromide   6159-05-3 DHBP is a calcium release inhibitor and a muscle relaxant.
CSN21592 Darodipine 72803-02-2 Darodipine is an antagonist of calcium channel.
CSN10744 Dantrolene sodium hemiheptahydrate   24868-20-0 Dantrolene Sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.
CSN20956 Cycleanine 518-94-5 Cycleanine, isolated from stephania, is a selective antagonist of vascular calcium.
CSN26332 Carboxyamidotriazole 99519-84-3 Carboxyamidotriazole is a blocker of non-voltage dependent calcium channel with anti-inflammatory activity.
CSN26603 Barnidipine 104713-75-9 Barnidipine is a calcium channel blocker.
CSN27668 Azumolene 64748-79-4 Azumolene, an analog of dantrolene, is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum by modulating the activity of the SR ryanodine receptor (RyR) Ca2+ release channel.
CSN10368 Azelnidipine   123524-52-7 Azelnidipine is a dihydropyridine L-type calcium channel blocker and an antihypertensive.
CSN24052 ACT-709478 1838651-58-3 ACT 709478 is a potent, selective, orally-bioavailable and brain penetrant T-type calcium channel blocker with IC50 of 6.4, 18, and 7.5 nM for Cav3.1, Cav3.2, and Cav3.3 channels respectively.
CSN27385 1-Octanol 111-87-5 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol is a highly attractive biofuel with diesel-like properties.
CSN14536 1-Hydroxy-2,3,5-Trimethoxyxanthone 22804-49-5 1-Hydroxy-2, 3, 5-trimethoxyxanthone, a natural product isolated and purified from the herb of Halenia elliptica D.
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