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Calcium Channel
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN18679 | Zonisamide | 68291-97-4 | Zonisamide, a 1,2 benzisoxazole derivative, is developed as an antiepileptic drug. |
| CSN18390 | Zonisamide sodium | 68291-98-5 | Zonisamide sodium is a 1,2 benzisoxazole derivative and the first agent of this chemical class to be developed as an antiepileptic drug. |
| CSN25647 | Verapamil | 52-53-9 | Verapamil is a phenylalkylamine class L-type calcium channel blocker. It may be a potential Covid-19 drug. |
| CSN27384 | Urolithin C | 165393-06-6 | Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation. |
| CSN16638 | Taurine | 107-35-7 | Taurine is a widely distributed organic compound in animal tissues which possesses function of conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization, and modulation of calcium signaling. |
| CSN22176 | 18:0 LYSO-PE | 69747-55-3 | Stearoyl lysophosphatidylethanolamine is an agent that can induce Ca2i increase. |
| CSN24655 | SAK3 | 1256269-87-0 | SAK 3 is a effective activator of CaV3.1 and CaV3.3. |
| CSN20495 | S107 | 927871-76-9 | S107 is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant andor PKA-phosphorylated channels. |
| CSN24653 | Ryanodine | 15662-33-6 | Ryanodine is an inhibitor of Ca2+ release from sarcoplasmic reticulum with IC50 values of 10 and 2.8 nM in skeletal and cardiac muscle respectively. |
| CSN13104 | Ranolazine | 95635-55-5 | Ranolazine inhibits calcium uptake via the sodiumcalcium channel, is used to treat chronic angina. |
| CSN12787 | Ranolazine dihydrochloride | 95635-56-6 | Ranolazine 2HCl is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina. |
| CSN29534 | Pranidipine | 99522-79-9 | Pranidipine is an effective, long-acting 1,4-dihydropyridine calcium channel blocker. It also has antihypertensive activity. |
| CSN27750 | NS-638 | 150493-34-8 | NS-638 is nonpeptide Ca2+-channel blocker with IC50 value of 3.4μM for blocking K+-stimulated intracellular Ca2+-elevation. |
| CSN11560 | Nilvadipine | 75530-68-6 | Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM. |
| CSN11555 | Nifedipine | 21829-25-4 | Nifedipine is a dihydropyridine calcium channel blocker used to lower hypertension and to treat angina |
| CSN11401 | Nicardipine hydrochloride | 54527-84-3 | Nicardipine HCl is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage. |
| CSN16159 | Neomycin sulfate | 28002-70-2 | Neomycin Trisulfate Salt is an aminoglycoside antibiotic and calcium channel protein inhibitor. |
| CSN11406 | Methyl 3,4,5-Trimethoxycinnamate | 7560-49-8 | Methyl 3,4,5-trimethoxycinnamate, a natural product isolated and purified from the herbs of Alstonia yunnanensis, may protect the heart from arrhythmias via its inhibitory effect on calcium channel. |
| CSN27383 | Levamlodipine | 103129-82-4 | Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina. |
| CSN21704 | Lemildipine | 94739-29-4 | Lemildipine is a 1,4-dihydropyridine calcium channel blocker which has potential to treat hypertension and cerebrovascular ischemia. |
| CSN12998 | Lamotrigine | 84057-84-1 | Lamotrigine is a member of the sodium channel blocking class of antiepileptic drugs which can block L-, N-, and P-type calcium channels and has weak 5-HT3 receptor inhibition. |
| CSN21683 | Iganidipine | 119687-33-1 | Iganidipine is a blocker of calcium channel that used for the treatment of glaucoma. |
| CSN16274 | Fraxinellone | 28808-62-0 | Fraxinellone, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz. with neuroprotective, vasorelaxing, insecticidal, and antimicrobial activities, is a selective blocker of voltage-dependent Ca2 channel, while dictamine relaxed the rat aorta by suppressing the Ca2 influx through both voltage-dependent and receptor-operated Ca2 channels, and can dramatically induce apoptosis of activated peripheral CD4() T cells in vivo, consequently resulting in less CD4() T-cell activation and infiltration to the liver. |
| CSN17326 | Felodipine | 72509-76-3 | Felodipine is a long-acting 14-dihydropyridine calcium channel blocker |
| CSN10948 | Ethosuximide | 77-67-8 | Ethosuximide is used to treat absence seizures. |
| CSN16302 | Efonidipine | 111011-63-3 | Efonidipine is a dual T-type and L-type calcium channel blocker (CCB). |
| CSN21615 | Dopropidil | 79700-61-1 | Dopropidil is a modulator of intracellular calcium with antagonist activity and anti-anginal effects. |
| CSN20804 | DHBP dibromide | 6159-05-3 | DHBP is a calcium release inhibitor and a muscle relaxant. |
| CSN21592 | Darodipine | 72803-02-2 | Darodipine is an antagonist of calcium channel. |
| CSN10744 | Dantrolene sodium hemiheptahydrate | 24868-20-0 | Dantrolene Sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. |
| CSN20956 | Cycleanine | 518-94-5 | Cycleanine, isolated from stephania, is a selective antagonist of vascular calcium. |
| CSN26332 | Carboxyamidotriazole | 99519-84-3 | Carboxyamidotriazole is a blocker of non-voltage dependent calcium channel with anti-inflammatory activity. |
| CSN26603 | Barnidipine | 104713-75-9 | Barnidipine is a calcium channel blocker. |
| CSN27668 | Azumolene | 64748-79-4 | Azumolene, an analog of dantrolene, is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum by modulating the activity of the SR ryanodine receptor (RyR) Ca2+ release channel. |
| CSN24052 | ACT-709478 | 1838651-58-3 | ACT 709478 is a potent, selective, orally-bioavailable and brain penetrant T-type calcium channel blocker with IC50 of 6.4, 18, and 7.5 nM for Cav3.1, Cav3.2, and Cav3.3 channels respectively. |
| CSN27385 | 1-Octanol | 111-87-5 | 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol is a highly attractive biofuel with diesel-like properties. |
| CSN14536 | 1-Hydroxy-2,3,5-Trimethoxyxanthone | 22804-49-5 | 1-Hydroxy-2, 3, 5-trimethoxyxanthone, a natural product isolated and purified from the herb of Halenia elliptica D. |
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