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Calcium Channel

Calcium Channel

Cat. No. Product Name CAS No. Information
CSN18679 Zonisamide   68291-97-4 Zonisamide, a 1,2 benzisoxazole derivative, is developed as an antiepileptic drug.
CSN18390 Zonisamide Sodium 68291-98-5 Zonisamide sodium is a 1,2 benzisoxazole derivative and the first agent of this chemical class to be developed as an antiepileptic drug.
CSN25647 Verapamil 52-53-9 Verapamil is a phenylalkylamine class L-type calcium channel blocker. It may be a potential Covid-19 drug.
CSN27384 Urolithin C 165393-06-6 Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation.
CSN24653 Ryanodine 15662-33-6 Ryanodine is an inhibitor of Ca2+ release from sarcoplasmic reticulum with IC50 values of 10 and 2.8 nM in skeletal and cardiac muscle respectively.
CSN23345 Ruthenium Red 11103-72-3 Ruthenium red a polycationic dye is an inhibitor of voltage sensitive calcium channel and used in histology to stain aldehyde fixed
CSN13104 Ranolazine   95635-55-5 Ranolazine inhibits calcium uptake via the sodiumcalcium channel, is used to treat chronic angina.
CSN29534 Pranidipine 99522-79-9 Pranidipine is an effective, long-acting 1,4-dihydropyridine calcium channel blocker. It also has antihypertensive activity.
CSN19446 Penfluridol   26864-56-2 Penfluridol, a T-type calcium channel blocker, is a highly potent, first generation diphenylbutylpiperidine antipsychotic.
CSN27750 NS638 150493-34-8 NS-638 is nonpeptide Ca2+-channel blocker with IC50 value of 3.4μM for blocking K+-stimulated intracellular Ca2+-elevation.
CSN11560 Nilvadipine 75530-68-6 Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM.
CSN11555 Nifedipine   21829-25-4 Nifedipine is a dihydropyridine calcium channel blocker used to lower hypertension and to treat angina
CSN11401 Nicardipine HCl   54527-84-3 Nicardipine HCl is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.
CSN22225 NecroX-5 1383718-29-3 NecroX-5 is a derivative of the NecroX, reduces intracellular calcium concentration, and possesses anti-inflammatory and anti-cancer activity.
CSN11406 Methyl 3,4,5-Trimethoxycinnamate 7560-49-8 Methyl 3,4,5-trimethoxycinnamate, a natural product isolated and purified from the herbs of Alstonia yunnanensis, may protect the heart from arrhythmias via its inhibitory effect on calcium channel.
CSN27383 Levamlodipine   103129-82-4 Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina.
CSN21704 Lemildipine 94739-29-4 Lemildipine is a 1,4-dihydropyridine calcium channel blocker which has potential to treat hypertension and cerebrovascular ischemia.
CSN23827 Lanthanum(III) Chloride Heptahydrate 10025-84-0 Lanthanum(III) chloride heptahydrate is a calcium channel blocker.
CSN11261 Lacidipine   103890-78-4 Lacidipine is a L-type calcium channel blocker, used for treating high blood pressure.
CSN21683 Iganidipine 119687-33-1 Iganidipine is a blocker of calcium channel that used for the treatment of glaucoma. 
CSN16274 Fraxinellone 28808-62-0 Fraxinellone, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz. with neuroprotective, vasorelaxing, insecticidal, and antimicrobial activities, is a selective blocker of voltage-dependent Ca2 channel, while dictamine relaxed the rat aorta by suppressing the Ca2 influx through both voltage-dependent and receptor-operated Ca2 channels, and can dramatically induce apoptosis of activated peripheral CD4() T cells in vivo, consequently resulting in less CD4() T-cell activation and infiltration to the liver.
CSN11028 Flunarizine 2HCl   30484-77-6 Flunarizine 2HCl is a dual NaCa2 channel (T-type) blocker with neuroprotective property.
CSN17326 Felodipine   72509-76-3 Felodipine is a long-acting 14-dihydropyridine calcium channel blocker
CSN23604 Ethyl 3-Aminobenzoate methanesulfonate   886-86-2 Ethyl 3-Aminobenzoate Methanesulfonate a hydrophilic derivative of benzocaine is an anesthetic
CSN10948 Ethosuximide   77-67-8 Ethosuximide is used to treat absence seizures.
CSN16302 Efonidipine 111011-63-3 Efonidipine is a dual T-type and L-type calcium channel blocker (CCB).
CSN21615 Dopropidil 79700-61-1 Dopropidil is a modulator of intracellular calcium with antagonist activity and anti-anginal effects.
CSN10709 Disodium Cromoglycate   15826-37-6 Disodium Cromoglycate is an antiallergic drug.
CSN10823 Diltiazem HCl   33286-22-5 Diltiazem HCl is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.
CSN20804 DHBP   6159-05-3 DHBP is a calcium release inhibitor and a muscle relaxant.
CSN21592 Darodipine 72803-02-2 Darodipine is an antagonist of calcium channel.
CSN10744 Dantrolene Sodium Hemiheptahydrate   24868-20-0 Dantrolene Sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.
CSN26332 Carboxyamidotriazole 99519-84-3 Carboxyamidotriazole is a blocker of non-voltage dependent calcium channel with anti-inflammatory activity.
CSN22911 CaCCinh-A01   407587-33-1 CaCCinh-A01 is a dual inhibitor of TMEM16A and calcium-activated chloride channel CaCC with IC50s of 21 and 10 M respectively
CSN22110 Bepridil HCl 68099-86-5 Bepridil HCl is a calcium channel blocker with antianginal activity
CSN26603 Barnidipine 104713-75-9 Barnidipine is a calcium channel blocker.
CSN27668 Azumolene 64748-79-4 Azumolene, an analog of dantrolene, is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum by modulating the activity of the SR ryanodine receptor (RyR) Ca2+ release channel.
CSN10368 Azelnidipine   123524-52-7 Azelnidipine is a dihydropyridine L-type calcium channel blocker and an antihypertensive.
CSN21491 Anipamil 83200-10-6 Anipamil is blocker of long-acting calcium channel and it is used to treat cardiovascular disease.
CSN24052 ACT-709478 1838651-58-3 ACT 709478 is a potent, selective, orally-bioavailable and brain penetrant T-type calcium channel blocker with IC50 of 6.4, 18, and 7.5 nM for Cav3.1, Cav3.2, and Cav3.3 channels respectively.
CSN27385 1-Octanol 111-87-5 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol is a highly attractive biofuel with diesel-like properties.
CSN14536 1-Hydroxy-2,3,5-Trimethoxyxanthone 22804-49-5 1-Hydroxy-2, 3, 5-trimethoxyxanthone, a natural product isolated and purified from the herb of Halenia elliptica D.
CSN25371 Nifedipine   21829-25-4
CSN25373 Felodipine   72509-76-3
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