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Calcineurin

Cat. No. Product Name CAS No. Information
CSN37875 Voclosporin 515814-01-4 Voclosporin is a novel calcineurin inhibitor intended for prevention of organ graft rejection and treatment of lupus nephritis. It was approved by the U.S. Food and Drug Administration (FDA) for the treatment of lupus nephritis (LN) on January 22, 2021.
CSN12789 Tacrolimus monohydrate 109581-93-3 Tacrolimus is a potent immunosuppressive drug often administered to transplant recipient patients and exhibits a variety of adverse cardiovascular effects. Its mechanism of action involves the formation of a high affinity complex (Ki 0.2 nM) with FK-506 binding protein 12 (FKBP12).
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