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cGAS
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN23556 | RU.521 | 2262452-06-0 | RU-521 is a potent and selective cyclic GMP-AMP synthase cGAS inhibitor with Kd of 36.2 nM. |
| CSN23557 | PF-06928215 | 2378173-15-8 | PF-06928215 is a cyclic GMP-AMP synthase cGAS inhibitor with IC50 of 49 M in the presence of 1 mM ATP 03 mM GTP 100 nM 45-bp interferon-stimulatory dsDNA ISD |
| CSN25328 | IRAK4-IN-4 | 1850276-58-2 | IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor with IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with IC50 of 2.1 nM. |
| CSN26462 | G150 | 2369751-30-2 | G150 is a potent and highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor for repression of dsDNA-triggered interferon expression, with an IC50 of 10.2 nM[1]. |
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