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c-RET

c-RET

Cat. No. Product Name CAS No. Information
CSN26135 RETV804M kinase inhibitor 2414909-94-5 RETV804M kinase inhibitor is a selective c-RET (V804M) inhibitor with IC50 value of 20nM.
CSN27593 DUN73423 2414373-42-3 DUN73423 is a RET/KDR-Selective inhibitor of RETV804M Kinase with IC50 of 7 nM.
CSN28779 BT13 924537-98-4 BT13 acts as direct RetA agonists and interacts with GFRα1 at the allosteric site in GDNF-GFRα1-RetA complex. It was similar to NGF and ARTN in selectively promoting neurite outgrowth from the peptidergic class of adult sensory neurons in culture, but was opposite to ARTN in causing neurite elongation without affecting initiation.
CSN18365 AST-487 630124-46-8 AST-487 is a RET kinase inhibitor with IC50 of 880 nM inhibits RET autophosphorylation and activation of downstream effectors also inhibits Flt-3 with IC50 of 520 nM
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