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c-FMS

c-FMS

Cat. No. Product Name CAS No. Information
CSN12402 Linifanib 796967-16-3 Linifanib is a potent ATP-competitive VEGFRPDGFR inhibitor for KDR, CSF-1R, Flt-13 and PDGFR with IC50 of 4 nM, 3 nM, 3 nM4 nM and 66 nM respectively.
CSN16124 Ki20227   623142-96-1 Ki-20227 is a highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50 value of 2 nM, displaying 6 fold and 100 fold selectivity over VEGFR2 (IC5012 nM) and c-KitPDGFR (IC50451217 nM), respectively.
CSN19706 JNJ-40346527 1142363-52-7 JNJ-40346527 is an orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R) with potential antineoplastic activity.
CSN12714 GW2580 870483-87-7 GW2580 is a selective CSF-1R inhibitor for c-FMS with IC50 of 30 nM, 150- to 500-fold selective compared to b-Raf, CDK4, c-KIT, c-SRC, EGFR, ERBB24, ERK2, FLT-3, GSK3, ITK, JAK2 etc.
CSN21196 GENZ-882706 2070864-35-4 GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) inhibitor that intends to treat immune-mediated diseases and neurological diseases.
CSN13574 c-FMS Inhibitor 885704-21-2 c-FMS inhibitor is a c-Fms kinase inhibitor with a potential as anti-inflammatory agent and antirheumatic agent.
CSN15751 BLZ945 953769-46-5 BLZ945 is a highly selective and brain-penetrant inhibitor of CSF1R with IC50 of 1 nM and 3200-fold higher than its affinity for other kinases
CSN22609 AZ304   942507-42-8 AZ304 is an inhibitor of BRAF and can target many kinases The IC50s for wild type BRAF V600E mutant BRAF and wild type CRAF are 79 nM 38 nM and 68 nM respectively It can also inhibit p38 IC50 6 nM and CSF1R IC50 35 nM
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