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β-catenin

β-catenin

Cat. No. Product Name CAS No. Information
CSN17476 WAY-262611   1123231-07-1 WAY-262611 is an agonist of -Catenin and can increase bone formation rate with EC50 of 063 M
CSN19245 SKL2001   909089-13-0 SKL2001 is Wnt-catenin pathway agonist which interferes in the interaction of Axin-catenin
CSN20164 PP2A-β-Catenin Inhibitor CS-11 N/A PP2A--Catenin inhibitor CS-11 a small molecule inhibitor of PP2A--catenin signaling that limits both in vivo tumor growth and metastasis
CSN11650 Pamidronic Acid   40391-99-9 Pamidronic Acid is a an amino- bisphosphonate used to prevent bone loss and treat osteoporosis.
CSN20582 KY1220 292168-79-7 KY1220 inhibits Wnt-catenin pathway with IC50 of 21 M in HEK293 cells and it can destabilize both -catenin and Ras
CSN12696 (6S)-N-Benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide 868774-16-7 ICG-001 is an inhibitor of β-catenin/cyclic AMP responsive element binding protein binding protein (CBP)-mediated transcription with IC50 of 3 µM.
CSN14871 Boehmenan 57296-22-7 Boehmenan, a natural product isolated and purified from the herbs of Euphorbia hirta Linn., exhibits cytotoxicity against both Wnt-dependent (HCT116) and Wnt-independent (RKO) cells, and decreases the expression of full, cytosolic and nuclear β-catenin along with c-myc in STF/293 cells, suggesting that boehmenan may have inhibited the Wnt signal by decreasing β-catenin levels.
CSN20163 BC2059 1227637-23-1 beta-Catenin inhibitor BC2059 is efficacious as monotherapy or in combination with proteasome inhibitor bortezomib in multiple myeloma
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