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Autophagy
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN11588 | Sulfacetamide Sodium | 127-56-0 | Sulfacetamide sodium is a sulfonamide antibiotic that is used topically to treat skin infections and orally for urinary tract infections |
| CSN16665 | STF-62247 | 315702-99-9 | STF-62247 is an autophagy inducer in VHL-deficient renal cell carcinoma cells and shows selective toxicity and growth inhibition for cells with VHL deficiency VHL- compared to wild-type VHL |
| CSN17766 | SR-9011 | 1379686-29-9 | SR9011 is an agonist of REV-ERB with IC50 of 790 nM for REV-ERB and IC50 560 nM for REV-ERB |
| CSN13809 | Spautin-1 | 1262888-28-7 | Spautin-1 is inhibitor of USP10 and USP13 with IC50 of 06 and 07 M respectively its also a potent and specific autophagy inhibitor |
| CSN23843 | Sofalcone | 64506-49-6 | Sofalcone is an anti-ulcer chalcone derivative, it could induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium. |
| CSN17302 | SMER28 | 307538-42-7 | SMER28 is a small-molecule enhancer SMER of autophagy inducing autophagy independently of the mTOR pathway |
| CSN18619 | SMER18 | 944153-47-3 | SMER18 is a small molecule enhancer of rapamycin which act as a mTOR-independent autophagy inducer |
| CSN20231 | ROC-325 | 1859141-26-6 | ROC-325 is an inhibitor of autophagy with promising anti-leukemic activity which diminishes AML cell viability with the IC50 range of 07-22 M |
| CSN24043 | Metformin | 657-24-9 | Metformin is a widely used anti-diabetic drug has potential efficacy as an anti-cancer drug, decreasing hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). |
| CSN16694 | Metformin HCl | 1115-70-4 | Metformin hydrochloride a widely used anti-diabetic drug has potential efficacy as an anti-cancer drug decreasing hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver hepatic gluconeogenesis |
| CSN22556 | Lys05 | 1391426-24-6 | Lys05 is water soluble salt of Lys01 Lys05 shows potent antitumor activity as a single agent both in vitro and in vivo in multiple human cancer cell lines and xenograft models |
| CSN22904 | IITZ-01 | 1807988-47-1 | IITZ-01 is an inhibitor of lysosomotropic autophagy It can enhance autophagosome accumulation and inhibit autophagosomal degradation that finally resulting in the inhibition of autophagy |
| CSN11173 | Hydroxychloroquine Sulfate | 747-36-4 | Hydroxychloroquine sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus rheumatoid arthritis and other autoimmune inflammatory and dermatologic conditions Also acts as an inhibitor of autophagy and toll-like receptor TLR79 |
| CSN16598 | Corynoxine | 6877-32-3 | Corynoxine is an enantiomer of Corynoxine B and induces autophagy in different neuronal cell lines including N2a and SHSY-5Y cells |
| CSN18014 | Corynoxine B | 17391-18-3 | Corynoxine B is an oxindole alkaloid isolated from Uncaria rhynchophylla Miq Jacks Gouteng in Chinese and a Beclin-1-dependent autophagy inducer |
| CSN22545 | Autophinib | 1644443-47-9 | Autophinib is an ATP-competitive inhibitor of the VPS34 with IC50 of 19 nM also inhibitor of starvation- and Rapamycin-induced autophagy with IC50 of 40 and 90 nM respectively |
| CSN23318 | 3BDO | 890405-51-3 |
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