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Aromatase
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN24635 | YM511 | 148869-05-0 | YM 511 is an orally active, potent aromatase (CYP19) inhibitor with IC50 of 0.4 and 0.12 nM at rat ovary and human placenta cells respectively. |
| CSN15878 | Urolithin B | 1139-83-9 | Urolithin B is a natural product with anti-proliferative and antioxidant activity, which can penetrate the blood-brain barrier and may have neuroprotective effects against Alzheimer’s Disease.It inhibits aromatase activity in human placental microsomes and aromatase-sensitive MCF-7 (MCF-7aro) human breast cancer cells when used at concentrations of 47 and 4.7 µM, respectively. |
| CSN15677 | Obacunone | 751-03-1 | Obacunone, a natural product isolated and purified from the barks of Phellodendron chinense, has cytotoxicity in androgen-dependent human prostate cancer cells. Obacunone may have the potential to prevent estrogen-responsive breast cancer through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis. |
| CSN10978 | Fadrozole | 102676-47-1 | Fadrozole is a selective aromatase inhibitor that has been introduced in Japan for the treatment of breast cancer |
| CSN19726 | Fadrozole hydrochloride | 102676-31-3 | Fadrozole HCl specifically inhibits aromatase, blocking the aromatization of androstenedione and testosterone into estrone and estradiol, respectively. |
| CSN27370 | Endoxifen | 110025-28-0 | Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. |
| CSN12252 | Chrysin | 480-40-0 | Chrysin, an analog of apigenin, demonstrates inhibition of aromatase and the phosphorylation of PLCY2 and PKC activities. It can be isolated from the blue passion flower (passiflora caerulea) with anti-inflammatory and anti-thrombotic activities etc.. |
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