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Apoptosis Inducer
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN13084 | Umbelliferone | 93-35-6 | Umbelliferone, a natural product isolated and purified from the herbs of Ruta graveolens L., exhibits significant anticancer effects via the induction of apoptosis, cell cycle arrest and DNA fragmentation in HepG2 cancer cells. |
| CSN21899 | 4H-Thiopyran-4-one,tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-,1,1-dioxide | 108477-18-5 | Ubiquitin Isopeptidase Inhibitor I, G5 is an apoptosome-independent caspase and apoptosis activator. |
| CSN29557 | TC11 | 100823-03-8 | TC11 is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9. |
| CSN15993 | Tasisulam | 519055-62-0 | Tasisulam is an antitumor agent and an apoptosis inducer via the intrinsic pathway. |
| CSN11797 | Pterostilbene | 537-42-8 | Pterostilbene is a natural dietary compound with antioxidant, antiproliferative, antihyperglycemic and antidiabetic effect, and is also an apoptosis inducer. |
| CSN17239 | NSC348884 | 81624-55-7 | NSC348884 is a nucleophosmin NPM inhibitor inhibits cell proliferation and induce apoptosis in various cancer cell lines with IC50 values ranging from 14-4 M |
| CSN13525 | Notopterol | 88206-46-6 | Notopterol induces apoptosis and inhibits cell cycle-specific, its a natural product isolated and purified from the roots of Notopterygium incisum. |
| CSN24150 | 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one xhydrate | 654055-01-3 | Morin, a natural product isolated and purified from the root bark of Morus alba L., induces caspase-dependent apoptosis through extrinsic pathway by upregulating Fas receptor as well as through the intrinsic pathway by modulating Bcl-2 and IAP family members, and ROS generation. |
| CSN11375 | Meisoindigo | 97207-47-1 | Meisoindigo, a derivative of Indigo naturalis with anticancer activity, might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML). |
| CSN23859 | Kinetin riboside | 4338-47-0 | Kinetin riboside, a cytokinin analog, can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells with an IC50 of 2.5 μM. |
| CSN14103 | Kaurenoic acid | 6730-83-2 | Kaurenoic Acid is a natural product isolated and purified from the herbs of Croton antisyphiliticus with anti-inflammatory property, the mechanisms may through inhibition of iNOS and COX-2 expression. Kaurenoic acid is an inducer of apoptosis, which is part of the innate mechanism of cell defense against neoplasia. Kaurenoic acid from A. continentalis may be a useful agent for inhibiting the cariogenic properties of S. mutans. |
| CSN11248 | Karanjin | 521-88-0 | Karanjin, a natural product isolated and purified from the seeds of the karanja tree (Millettia pinnata or Pongamia glabra Vent.), has an effects on cell cycle arrest and apoptosis in human A549, HepG2 and HL-60 cancer cells. |
| CSN24957 | Geranyl acetate | 105-87-3 | Geranyl acetate is a natural organic compound that is used primarily as a component of perfumes for creams and soaps and as a flavoring ingredient. |
| CSN26400 | Flavokawain B | 1775-97-9 | Flavokawain B, a chalcone isolated from the root extracts of kava-kava plant, is a potent apoptosis inducer for inhibiting the growth of various cancer cell lines. Flavokawain B shows strong antiangiogenic activity and inhibits human brain endothelial cell (HUVEC) migration and tube formation with very low and non-toxic concentrations[1][2]. |
| CSN18396 | Episilvestrol | 697235-39-5 | Episilvestrol is a derivative of Silvestrol which can induce apoptosis in LNCaP cells through the mitochondrialapoptosome pathway without activation of executioner caspase-3 or -7 and a 5myc-UTR-LUC inhibtor IC50 08 nM |
| CSN18900 | (E)-[6]-Dehydroparadol | 878006-06-5 | E-6-Dehydroparadol shows growth inhibition and induction of apoptosis against human cancer cells with IC50 values of 4302 M in HCT-116 cell and 4159 M in H-1299 cell respectively |
| CSN23777 | BTR-1 | 18331-34-5 | BTR-1 is a rhodanine derivative induced cytotoxicity in a time- and concentration-dependent manner on leukemic cell line, leading to increased level of ROS production and DNA strand breaks suggesting activation of apoptosis for induction of cell death. |
| CSN25584 | Atractyloside potassium salt | 102130-43-8 | Atractyloside is a natural compound that acts both an inhibitor of ANT and an apoptosis inducer. |
| CSN12275 | Dihydrokaempferol | 480-20-6 | Aromadendrin, a natural product isolated and purified from the bark of Eucalyptus calophylla, has anti-diabetic, anti-inflammatory, and antioxidant effects. |
| CSN17056 | Apoptosis Activator 2 | 79183-19-0 | Apoptosis activator 2 is a potent apoptosis activator which increases procaspase-9 processing and subsequent caspase-3 activation |
| CSN18300 | Adarotene | 496868-77-0 | Adarotene is an effective apoptosis inducer and surprisingly produced DNA damage ST1926 exhibites a potent antiproliferative activity on a large panel of human tumor cells |
| CSN25117 | 2-methoxycinnamaldehyde | 1504-74-1 | 2-methoxycinnamaldehyde, found in ceylan cinnamon, is a flavouring ingredient. |
| CSN29107 | (-)-Epipodophyllotoxin | 4375-07-9 |
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