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Apoptosis Inducer
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN13590 | Trabectedin | 114899-77-3 | Trabectedin is an antitumour agent of marine origin with potent antitumour activity both in vitro and in vivo. |
| CSN11500 | SMIP004 | 143360-00-3 | SMIP004 is an inducer of cancer-cell selective apoptosis of human prostate cancer cells downregulates SKP2 and stabilizes p27 |
| CSN13728 | Silvestrol | 697235-38-4 | Silvestrol is isolated from the fruits and twigs of Aglaia foveolata by inducing caspase-3 activation to cause cell death |
| CSN18642 | Silvestrol Aglycone | 960365-65-5 | Silvestrol aglycone an aglycone of potential anticancer rocaglate derivative from Aglaia foveolata induces apoptosis in LNCaP cells through the mitochondrialapoptosome pathway without activation of executioner caspase-3 or -7 and a 5myc-UTR-LUC inhibtior IC50 08 nM |
| CSN17239 | NSC 348884 | 81624-55-7 | NSC348884 is a nucleophosmin NPM inhibitor inhibits cell proliferation and induce apoptosis in various cancer cell lines with IC50 values ranging from 14-4 M |
| CSN18325 | Methyl Protodioscin | 54522-52-0 | Methyl protodioscin is a furostanol bisglycoside with antitumor properties and shows to reduce proliferation, cause cell cycle arrest. |
| CSN11375 | Meisoindigo | 97207-47-1 | Meisoindigo, a derivative of Indigo naturalis with anticancer activity, might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML). |
| CSN19280 | Jesridonin | 2074768-37-7 | Jesridonin has synergistic apoptosis-induction effects with paclitaxel mediated by the mitochondrial pathway |
| CSN12309 | Isoalantolactone | 470-17-7 | Isoalantolactone is a naturally occuring sesquiterpene lactone isolated from Inula helenium with a role as an apoptosis inducer an antifungal agent and a plant metabolite |
| CSN20583 | FIN56 | 1083162-61-1 | FIN56 is a ferroptosis activator and glutathione peroxidase 4 GPX4 degradation inducer It also bound to and activated squalene synthase SQS an enzyme involved in isoprenoid biosynthesis |
| CSN18396 | Episilvestrol | 697235-39-5 | Episilvestrol is a derivative of Silvestrol which can induce apoptosis in LNCaP cells through the mitochondrialapoptosome pathway without activation of executioner caspase-3 or -7 and a 5myc-UTR-LUC inhibtor IC50 08 nM |
| CSN16025 | Epibrassinolide | 78821-43-9 | Epibrassinolide is a biologically active compound of the brassinosteroids, steroid-derived plant growth regulator family, and is shown as a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth. |
| CSN18900 | (E)-[6]-Dehydroparadol | 878006-06-5 | E-6-Dehydroparadol shows growth inhibition and induction of apoptosis against human cancer cells with IC50 values of 4302 M in HCT-116 cell and 4159 M in H-1299 cell respectively |
| CSN18261 | Desacetylcinobufotalin | 4099-30-3 | Desacetylcinobufotalin is a natural apoptosis inducer and shows the marked inhibition effect to HepG2 cells and the IC50 value is 00279 molmL |
| CSN20352 | BDE-47 | 5436-43-1 | BDE-47 (2,2',4,4'-Tetrabromodiphenyl Ether) is an apoptosis inducer involving ROS mediated mitochondrial pathway and Nrf2 pathway activation. |
| CSN17056 | Apoptosis Activator 2 | 79183-19-0 | Apoptosis activator 2 is a potent apoptosis activator which increases procaspase-9 processing and subsequent caspase-3 activation |
| CSN18300 | Adarotene | 496868-77-0 | Adarotene is an effective apoptosis inducer and surprisingly produced DNA damage ST1926 exhibites a potent antiproliferative activity on a large panel of human tumor cells |
| CSN10645 | 9-beta-Arabinosylguanine | 38819-10-2 | 9-beta-Arabinosylguanine is an inducer of apoptosis inhibitor of DNA synthesis an antimetabolite and antineoplastic |
| CSN13311 | 3-O-Acetyloleanolic Acid | 4339-72-4 | 3-O-Acetyloleanolic Acid exhibits anti-angiogenic effects and induces apoptosis in HUVECs and HCT-116 cells it is a natural product isolated and purified from the herbs of Phytolacca americana |
| CSN23859 | Kinetin Riboside | 4338-47-0 |
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