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Apoptosis Inducer

Apoptosis Inducer

Cat. No. Product Name CAS No. Information
CSN13590 Trabectedin 114899-77-3 Trabectedin is an antitumour agent of marine origin with potent antitumour activity both in vitro and in vivo.
CSN11500 SMIP004 143360-00-3 SMIP004 is an inducer of cancer-cell selective apoptosis of human prostate cancer cells downregulates SKP2 and stabilizes p27
CSN13728 Silvestrol 697235-38-4 Silvestrol is isolated from the fruits and twigs of Aglaia foveolata by inducing caspase-3 activation to cause cell death
CSN18642 Silvestrol Aglycone 960365-65-5 Silvestrol aglycone an aglycone of potential anticancer rocaglate derivative from Aglaia foveolata induces apoptosis in LNCaP cells through the mitochondrialapoptosome pathway without activation of executioner caspase-3 or -7 and a 5myc-UTR-LUC inhibtior IC50 08 nM
CSN17239 NSC 348884   81624-55-7 NSC348884 is a nucleophosmin NPM inhibitor inhibits cell proliferation and induce apoptosis in various cancer cell lines with IC50 values ranging from 14-4 M
CSN18325 Methyl Protodioscin 54522-52-0 Methyl protodioscin is a furostanol bisglycoside with antitumor properties and shows to reduce proliferation, cause cell cycle arrest.
CSN11375 Meisoindigo   97207-47-1 Meisoindigo, a derivative of Indigo naturalis with anticancer activity, might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML).
CSN19280 Jesridonin 2074768-37-7 Jesridonin has synergistic apoptosis-induction effects with paclitaxel mediated by the mitochondrial pathway
CSN12309 Isoalantolactone   470-17-7 Isoalantolactone is a naturally occuring sesquiterpene lactone isolated from Inula helenium with a role as an apoptosis inducer an antifungal agent and a plant metabolite
CSN20583 FIN56 1083162-61-1 FIN56 is a ferroptosis activator and glutathione peroxidase 4 GPX4 degradation inducer It also bound to and activated squalene synthase SQS an enzyme involved in isoprenoid biosynthesis
CSN18396 Episilvestrol 697235-39-5 Episilvestrol is a derivative of Silvestrol which can induce apoptosis in LNCaP cells through the mitochondrialapoptosome pathway without activation of executioner caspase-3 or -7 and a 5myc-UTR-LUC inhibtor IC50 08 nM
CSN16025 Epibrassinolide 78821-43-9 Epibrassinolide is a biologically active compound of the brassinosteroids, steroid-derived plant growth regulator family, and is shown as a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth.
CSN18900 (E)-[6]-Dehydroparadol 878006-06-5 E-6-Dehydroparadol shows growth inhibition and induction of apoptosis against human cancer cells with IC50 values of 4302 M in HCT-116 cell and 4159 M in H-1299 cell respectively
CSN18261 Desacetylcinobufotalin 4099-30-3 Desacetylcinobufotalin is a natural apoptosis inducer and shows the marked inhibition effect to HepG2 cells and the IC50 value is 00279 molmL
CSN20352 BDE-47 5436-43-1 BDE-47 (2,2',4,4'-Tetrabromodiphenyl Ether) is an apoptosis inducer involving ROS mediated mitochondrial pathway and Nrf2 pathway activation.
CSN17056 Apoptosis Activator 2   79183-19-0 Apoptosis activator 2 is a potent apoptosis activator which increases procaspase-9 processing and subsequent caspase-3 activation
CSN18300 Adarotene 496868-77-0 Adarotene is an effective apoptosis inducer and surprisingly produced DNA damage ST1926 exhibites a potent antiproliferative activity on a large panel of human tumor cells
CSN10645 9-beta-Arabinosylguanine 38819-10-2 9-beta-Arabinosylguanine is an inducer of apoptosis inhibitor of DNA synthesis an antimetabolite and antineoplastic
CSN13311 3-O-Acetyloleanolic Acid 4339-72-4 3-O-Acetyloleanolic Acid exhibits anti-angiogenic effects and induces apoptosis in HUVECs and HCT-116 cells it is a natural product isolated and purified from the herbs of Phytolacca americana
CSN23859 Kinetin Riboside 4338-47-0
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