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Apoptosis Inducer
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN12434 | Tetrahydrocurcumin | 36062-04-1 | Tetrahydrocurcumin, a natural product isolated and purified from the rhizomes of Curcuma longa L., is one of the major metabolites of Curcumin. It is an apoptosis inducer and has been demonstrated to be an antioxidant. |
| CSN11911 | Securinine | 5610-40-2 | Securinine, a natural product isolated and purified from the leaves and twigs of Securinega suffruticosa with antifungal activity, induces apoptosis in human leukemia HL-60 cells, is a promising monocytic differentiation inducing agent for Acute Myeloid Leukemia (AML). |
| CSN11797 | Pterostilbene | 537-42-8 | Pterostilbene is a natural dietary compound with antioxidant, antiproliferative, antihyperglycemic and antidiabetic effect, and is also an apoptosis inducer. |
| CSN17239 | NSC 348884 | 81624-55-7 | NSC348884 is a nucleophosmin NPM inhibitor inhibits cell proliferation and induce apoptosis in various cancer cell lines with IC50 values ranging from 14-4 M |
| CSN11375 | Meisoindigo | 97207-47-1 | Meisoindigo, a derivative of Indigo naturalis with anticancer activity, might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML). |
| CSN14103 | Kaurenoic Acid | 6730-83-2 | Kaurenoic Acid is a natural product isolated and purified from the herbs of Croton antisyphiliticus with anti-inflammatory property, the mechanisms may through inhibition of iNOS and COX-2 expression. Kaurenoic acid is an inducer of apoptosis, which is part of the innate mechanism of cell defense against neoplasia. Kaurenoic acid from A. continentalis may be a useful agent for inhibiting the cariogenic properties of S. mutans. |
| CSN12309 | Isoalantolactone | 470-17-7 | Isoalantolactone is a naturally occuring sesquiterpene lactone isolated from Inula helenium with a role as an apoptosis inducer an antifungal agent and a plant metabolite |
| CSN19958 | Columbianadin | 5058-13-9 | Columbianadin, a natural product isolated and purified from the herbs of Angelicae pubescens with analgesic, anti-inflammatory, calcium-channel blocking, and platelet aggregation inhibiting functions, can effectively suppress the growth of colon cancer cells, low concentration (up to 25 μM) of CBN induces apoptosis, and high concentration (50 μM) of CBN induces necroptosis, demonstrates that CBN has the potential to be a candidate in the development of anti-cancer agent derived from natural products. |
| CSN23777 | BTR-1 | 18331-34-5 | BTR-1 is a rhodanine derivative induced cytotoxicity in a time- and concentration-dependent manner on leukemic cell line, leading to increased level of ROS production and DNA strand breaks suggesting activation of apoptosis for induction of cell death. |
| CSN25584 | Atractyloside potassium salt | 102130-43-8 | Atractyloside is a natural compound that acts both an inhibitor of ANT and an apoptosis inducer. |
| CSN12275 | Aromadendrin | 480-20-6 | Aromadendrin, a natural product isolated and purified from the bark of Eucalyptus calophylla, has anti-diabetic, anti-inflammatory, and antioxidant effects. |
| CSN17056 | Apoptosis Activator 2 | 79183-19-0 | Apoptosis activator 2 is a potent apoptosis activator which increases procaspase-9 processing and subsequent caspase-3 activation |
| CSN10645 | 9-beta-Arabinosylguanine | 38819-10-2 | 9-beta-Arabinosylguanine is an inducer of apoptosis inhibitor of DNA synthesis an antimetabolite and antineoplastic |
| CSN13311 | 3-O-Acetyloleanolic Acid | 4339-72-4 | 3-O-Acetyloleanolic Acid exhibits anti-angiogenic effects and induces apoptosis in HUVECs and HCT-116 cells it is a natural product isolated and purified from the herbs of Phytolacca americana |
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