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AP-1 (activating protein-1) is a collective term referring to dimeric transcription factors composed of Jun, Fos or ATF (activating transcription factor) subunits that bind to a common DNA site, the AP-1-binding site.


Cat. No. Product Name CAS No. Information
CSN18329 PNRI-299 550368-41-7 PNRI-299 is a selective AP-1 transcription inhibitor with IC50 of 20 M without affecting NF-kappaB transcription (up to 200 M) or thioredoxin (up to 200 M).
CSN20807 Ganoderenic acid B 100665-41-6 Ganoderic acid, a triterpene found in Ganoderma mushrooms, is reported to exhibit anti-tumor activity mediated through its inhibitory effect on NFKB and AP-1 as well as antimetastasis and anti-HIV activities.
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