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AP-1 (activating protein-1) is a collective term referring to dimeric transcription factors composed of Jun, Fos or ATF (activating transcription factor) subunits that bind to a common DNA site, the AP-1-binding site.


Cat. No. Product Name CAS No. Information
CSN18329 PNRI-299 550368-41-7 PNRI-299 is a selective AP-1 transcription inhibitor with IC50 of 20 M without affecting NF-kappaB transcription (up to 200 M) or thioredoxin (up to 200 M).
CSN27551 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid 3719-45-7 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is from Cordyceps bassiana, which is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function.
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