AP-1 (activating protein-1) is a collective term referring to dimeric transcription factors composed of Jun, Fos or ATF (activating transcription factor) subunits that bind to a common DNA site, the AP-1-binding site.
|Cat. No.||Product Name||CAS No.||Information|
|CSN18329||PNRI-299||550368-41-7||PNRI-299 is a selective AP-1 transcription inhibitor with IC50 of 20 M without affecting NF-kappaB transcription (up to 200 M) or thioredoxin (up to 200 M).|
|CSN20807||Ganoderenic acid B||100665-41-6||Ganoderic acid, a triterpene found in Ganoderma mushrooms, is reported to exhibit anti-tumor activity mediated through its inhibitory effect on NFKB and AP-1 as well as antimetastasis and anti-HIV activities.|