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Amyloid-β

Amyloid-β

Cat. No. Product Name CAS No. Information
CSN13757 Tramiprosate   3687-18-1 Tramiprosate targets soluble A to decrease amyloid plaque deposition and maintains A in a non-fibrillar form.
CSN20304 PE859 1402727-29-0 PE859 is a Curcumin-derived inhibitor of Amyloid- and Tau aggregation and can ameliorate cognitive dysfunction in senescence-accelerated mouse Prone 8
CSN21321 MK-3328 1201323-97-8 MK-3328 is a -Amyloid PET ligand which exhibits high binding potency with an IC50 of 105 nM
CSN13820 MK-0752 471905-41-6 MK-0752 is a moderately potent -secretase inhibitor which reduces A40 production with IC50 of 5 nM
CSN15566 Mirabijalone D 485811-84-5 Mirabijalone D, a natural product isolated and purified from Abronia nana, is a non-competitive inhibitor based on the Dixon plot, and inhibits A142 production by 43.7 in APPSW-N2a cells.
CSN18386 K 01-162 677746-25-7 K 01-162 binds and destabilizes AO -amyloid with an EC50 of 80 nM
CSN23629 HP-β-CD   128446-35-5 HP--CD is used to improve the solubility of lipophilic drugs It is also an inhibitor of amyloid- aggregation and A-induced toxicity
CSN19481 Ginsenoside Rg1   22427-39-0 Ginsenoside Rg1, a natural product isolated and purified from the roots of Panax ginseng C. A. Mey., is a functional ligand of glucocorticoid receptor(GR) that can boost the production of insulin receptors, stimulates the creation of new blood vessels and wound healing, relaxes and widens blood vessels and lowers blood pressure, and is a potent phytoestrogen with estrogen-like activity.
CSN11056 Frentizole 26130-02-9 Frentizole, an immunosuppressive drug, is an inhibitor of the A-ABAD interaction.
CSN17194 FPS-ZM1   945714-67-0 FPS-ZM1 is a high-affinity RAGE-specific inhibitor that blocks Aβ binding to the V domain of RAGE with Ki of 25 ± 5 nM in RAGE-transfected CHO cells.
CSN11884 EUK 134 81065-76-1 EUK 134 a synthetic superoxide dismutase SODcatalase mimetic exhibits potent antioxidant activities and inhibits the formation of -amyloid and related amyloid fibril
CSN23229 Edonerpic Maleate 519187-97-4 Edonerpic maleate can inhibitamyloid- peptidesA and used as a neurotrophic agent
CSN21120 DWK-1339 1018946-38-7 DWK-1339 is an orally active and blood-brain-barrier-permeable A-aggregation inhibitor used in the research of Alzheimers disease
CSN17400 ARN2966 102212-26-0 ARN2966 is a potent post-transcriptional modulator of APP expression and reduces expression of APP with resultant lower production of A
CSN19128 Amyloid P-IN-1 1819986-22-5 Amyloid P-IN-1 is a potential compound for treating amyloidosis Alzheimers disease type 2 diabetes mellitus and osteoarthritis
CSN21167 Aftin-4 866893-90-5 Aftin-4 is a potent and selective A42 inducer with an EC50 of 30 M
CSN21189 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine 566169-98-0 4-6-Bromo-2-benzothiazolyl-N-methylbenzenamine is a potent amyloid imaging agent which binds to Amyloid- 1-40 with a KD of 17 nM
CSN22036 4-(6-Bromo-2-benzothiazolyl)benzenamine 566169-97-9 4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET (positron emission tomography) tracer that can be used in the diagnosis of neurological diseases, such as Alzheimer's and Down's syndrome.
CSN20235 2-D08   144707-18-6 2-D08 interacts with amyloid β, showing an anti-aggregatory and neuroprotective effect.
CSN23259 CRANAD 2 1193447-34-5
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