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Amyloid-β

Amyloid-β

Cat. No. Product Name CAS No. Information
CSN13757 Tramiprosate   3687-18-1 Tramiprosate targets soluble A to decrease amyloid plaque deposition and maintains A in a non-fibrillar form.
CSN18386 K 01-162 677746-25-7 K 01-162 binds and destabilizes AO -amyloid with an EC50 of 80 nM
CSN23629 HP-β-CD   128446-35-5 HP--CD is used to improve the solubility of lipophilic drugs It is also an inhibitor of amyloid- aggregation and A-induced toxicity
CSN19488 Ginsenoside Re 52286-59-6 Ginsenoside Re is a panaxatriol saponin that has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions.
CSN11056 Frentizole 26130-02-9 Frentizole, an immunosuppressive drug, is an inhibitor of the A-ABAD interaction.
CSN17194 FPS-ZM1   945714-67-0 FPS-ZM1 is a high-affinity RAGE-specific inhibitor that blocks Aβ binding to the V domain of RAGE with Ki of 25 ± 5 nM in RAGE-transfected CHO cells.
CSN11884 EUK 134 81065-76-1 EUK 134 a synthetic superoxide dismutase SODcatalase mimetic exhibits potent antioxidant activities and inhibits the formation of -amyloid and related amyloid fibril
CSN23259 CRANAD 2 1193447-34-5 CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits. Upon interacting with Abeta aggregates, CRANAD-2 undergoes a range of changes, which include a 70-fold fluorescence intensity increase, a 90 nm blue shift (from 805 to 715 nm), and a large increase in quantum yield. Moreover, this probe also shows a high affinity for Abeta aggregates (K(d) = 38.0 nM), a reasonable log P value (log P = 3), considerable stability in serum, and a weak interaction with albumin. After intravenous injection of this probe, 19-month-old Tg2576 mice exhibited significantly higher relative signal than that of the control mice over the same period of time.
CSN17400 ARN2966 102212-26-0 ARN2966 is a potent post-transcriptional modulator of APP expression and reduces expression of APP with resultant lower production of A
CSN19128 Amyloid P-IN-1 1819986-22-5 Amyloid P-IN-1 is a potential compound for treating amyloidosis Alzheimers disease type 2 diabetes mellitus and osteoarthritis
CSN21167 Aftin-4 866893-90-5 Aftin-4 is a potent and selective A42 inducer with an EC50 of 30 M
CSN22036 4-(6-Bromo-2-benzothiazolyl)benzenamine 566169-97-9 4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET (positron emission tomography) tracer that can be used in the diagnosis of neurological diseases, such as Alzheimer's and Down's syndrome.
CSN20235 2-D08   144707-18-6 2-D08 interacts with amyloid β, showing an anti-aggregatory and neuroprotective effect.
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