|γDGG is a blocker of AMPA receptor.
|ZK200775 is a highly selective AMPAkainate antagonist with little activity against NMDA with Ki values of 3.2 nM, 100 nM, and 8.5 M against quisqualate, kainate, and NMDA, respectively.
|ZK200775 is a highly selective AMPAkainate antagonist with little activity against NMDA and has Ki values of 3.2 nM, 100 nM, and 8.5 M against quisqualate, kainate, and NMDA, respectively.
|YM 872 is an AMPA receptor antagonists and acts as antiepileptic drugs.
|UBP-282 is an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and kainate receptor antagonist.
|UBP 310 is an antagonist of GluK1 (formerly GLUK5) kainate receptor with IC50 of 130 nM.
|UBP 302 is a potent and selective GluK1 (formally GluR5)-subunit containing kainate receptor antagonist with KD of 402 nM.
|U-54494A hydrochloride is a selective non-competitive AMPA receptor antagonist with IC50 of 10-20 mM.
|Sunifiram is a piperazine derived ampakine-like drug(acting via AMPA receptors) which has nootropic effects in animal studies with significantly higher potency than piracetam.
|Selurampanel is a competitive AMPAkainate receptor antagonist drug for epilepsy
|S-Willardiine is a potent agonist of AMPAkainate receptors with EC50 of 448 M
|RS-AMPA hydrobromide is a class of glutamate agonist structurally related to ibotenic acid
|Philanthotoxin 74 2HCl
|Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively.
|PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells
|PF-04958242 is an AMPA receptor positive allosteric modulator.
|PEPA is an allosteric modulator of AMPA receptors and binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity
|NPEC-caged-(S)-AMPA is an agonist at the AMPA receptor.
|Noopept is a potent nootropic that improves cognitive ability.
|NBQX is a potent, selective and competitive AMPAR antagonist, which shows activity of neuroprotective and anticonvulsant.
|NBQX Disodium Salt is a potent, selective and competitive AMPA receptor antagonist.
|LY3130481 is the the first -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid AMPA receptor antagonist that is dependent on the presence of TARP -8 LY3130481 is fully protective against pentylenetetrazole-induced convulsions in rats without the motor impairment associated with non-TARP-dependent AMPA receptor antagonists
|L-theanine is an amino acid found most commonly in tea leaves and binds to ionotropic glutamate receptors in the micromolar range including the AMPA and kainate receptors and to a lesser extent the NMDA receptor
|Kynurenic Acid is a broad spectrum glutamatergic antagonist which can antagonize NMDA kainate and AMPA receptors
|JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8. Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy in mouse hippocampus, resulting in robust seizure protection in corneal kindling and pentylenetetrazole (PTZ) anticonvulsant models.
|IDRA-21 is a positive AMPA receptor modulator. IDRA-21 inhibits synaptic and extrasynaptic NMDA receptor mediated events in cultured cerebellar granule cells. IDRA 21 enhances ischemic hippocampal neuron injury.
|GYKI 52466 2HCl is a selective non-competitive AMPA receptor antagonist with IC50 of 10-20 μM.
|Glutamate receptor agonist acting at AMPA receptors and metabotropic glutamate receptors positively linked to phosphoinositide hydrolysis Sensitizes neurons in hippocampus to depolarization by L-AP6 the so called quis effect
|Farampator (CX-691;Org24448) is an AMPA receptor positive modulator.
|CX 614 is a positive allosteric modulator of AMPA receptors.
|CP 465022 HCl is a selective, non-competitive AMPA receptor antagonist (IC50 = 25 nM in rat cortical neurons) that displays potent anticonvulsant activity.
|Coluracetam a nootropic which can increase the potency of AMPA receptors.
|CNQX is a potent and selective non-NMDA iGluR antagonist
|ATPA is a selective and potent GluK1 kainate receptor agonist with Ki of 4.3 nM.
|Ampalex is a positive allosteric modulator of AMPAR and is researched as a treatment for Alzheimers disease.
|1-BCP is can modulate AMPA receptor gated currents and enhence memory.
|(S)-Glutamic acid acts as an excitatory neurotransmitter in the central nervous system.
|(S)-AMPA is a selective AMPA agonist.
|(R)-3,4-DCPG is a AMPA receptor antagonist.