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Alkaloids

Alkaloids

Cat. No. Product Name CAS No. Information
CSN12193 Vasicine 6159-55-3 Vasicine, a natural product isolated and purified from the leaves of Adhatoda vasica, is a potential cholinesterase inhibitor in development for treatment of Alzheimers disease, and can regulate the inflammatory reaction.
CSN12111 Tomatidine 77-59-8 Tomatidine, a natural product isolated and purified from the fruits of Lycopersicon esculentum Mill., shows antibiotic activity against small-colony variants of S. aureus, significantly suppresses the activity of ACAT and leads to reduction of atherogenesis. It also inhibits the phosphorylation of ERK, Akt, and the nuclear content of NF-B.
CSN11960 Solasodine   126-17-0 Solasodine is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family.
CSN20839 Senecionine 130-01-8 Senecionine is a pyrrolizidine alkaloid isolated from Senecio vulgaris. Senecionine is toxic to animals and humans.
CSN11905 Scoulerine 6451-73-6 Scoulerine, a natural product isolated and purified from the herbs of Corydalis dubia., shows significant cytotoxic effects against both two cancer cell lines (Caco-2 and Hep-G2 cancer cells), with IC50 values 6.44 0.87 and 4.57 0.42, respectively.
CSN14733 Scholaricine 99694-90-3 Scholaricine, a natural product isolated and purified from the herbs of Bothrocaryum controversum, reverses multidrug resistance in vincristine-resistant KB cells and may produce the anti-inflammatory and analgesic effect.
CSN14191 Robustine 2255-50-7 Robustine, a natural product isolated and purified from the stem wood of Zanthoxylum avicennae., exhibits inhibition (IC 50 or 18.19 mM) of superoxide anion generation by human neutrophils in response to formyl- l-methionyl- l-leucyl- l-phenylalaninecytochalasin B (FMLPCB), suggests that it may have anti-inflammatory activity.
CSN14146 Picralinal 20045-06-1 Picralinal is a natural product isolated and purified from the herbs of Alstonia scholaris with anti-inflammatory and analgesic effects.
CSN16182 Peiminine 18059-10-4 Peiminine, a natural product isolated and purified from the bulbus of Fritillaria thunbergii Miq., is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.
CSN11645 Palmatine 3486-67-7 Palmatine, a natural product isolated and purified from the rhizomes of Coptis chinensis Franch., is an inhibitor of dopamine generation. Palmatine could potentially be developed for the treatment of flavivirus infections.
CSN14543 Odorine 72755-20-5 Odorine, a natural product isolated and purified from the herbs of Aglaia odorata, has potent anti-carcinogenic effect by inhibiting both the initiation and promotion stages of two-stage skin carcinogenesis, and is found to inhibit the growth of the vinblastine-resistant KB cells by enhancing the anticancer activity of vinblastine.
CSN16615 Norisoboldine 23599-69-1 Norisoboldine is an isoquinoline alkaloid isolated and purfied from the roots of Lindera aggregata, which acts as an AhR agonist, and enhances the function of the adenosine A1 receptor.
CSN15023 Norglaucine HCl 39945-41-0 Norglaucine hydrochloride, a natural product isolated and purified from the stem of Xylopia laevigata, shows cytotoxic activity toward the tumor cell lines B16-F10 (mouse melanoma), HepG2 (human hepatocellular carcinoma), K562 (human chronic myelocytic leukemia) and HL-60 (human promyelocytic leukemia) and non-tumor peripheral blood mononuclear cells (PBMCs).
CSN19522 Nicotinic Acid   59-67-6 Nicotinic acid is a water-soluble vitamin and is part of the vitamin B group.
CSN11532 Neferine 2292-16-2 Neferine, is a major alkaloid present in the green embryos of Nelumbo nucifera Gaertn with anti-arrhythmia, anti-hypertensive and vaso-relaxant properties , and is also a NF-B inhibitor.
CSN19938 Magnoflorine Chloride 6681-18-1 Magnoflorine is a natural product isolated and purified from the flower of Magnolia liliiflora Desr. with anti-inflammatory activity.
CSN12376 Leonurine 24697-74-3 Leonurine is a pseudoalkaloid possessing anti-inflammatory properties and isolated from plants of family Lamiaceae.
CSN16150 K252a 99533-80-9 K252a is an alkaloid isolated from Nocardiopisis sp. soil fungi. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 1.8 and 1.7 nmolL, respectively).
CSN19466 Hypaconitine 6900-87-4 Hypaconitine, an active and highly toxic constituent derived from Aconitum species, is widely used to treat rheumatism.
CSN16832 Hydrastine 118-08-1 Hydrastine is a natural alkaloid which is present in Hydrastis canadensis and other plants of the ranunculaceae family.
CSN11120 Glutathione   70-18-8 Glutathione acts as an antioxidant, a free radical scavenger and a detoxifying agent. It is a tripeptide comprised of three amino acids (cysteine, glutamic acid, and glycine) present in most mammalian tissue.
CSN12902 Fumitremorgin C 118974-02-0 Fumitremorgin C is a chemosensitizing agent which selectively reverses BCRP-mediated multidrug resistance to mitoxantrone, doxorubicin and topotecan in transfected MCF-7 cells, but does not reverse resistance in P-gp- or MRP-positive cells.
CSN16848 Fangchinoline   436-77-1 Fangchinoline is an isolate of Stephania tetrandra and has anticancer activity through induction of G1 arrest in breast cancer cells.
CSN14167 Erysotrine 27740-43-8 Erysotrine is a natural product isolated and purified from the barks of Aralia chinensis with cytotoxic activity against Hep-G2.
CSN14176 Enniatin B 917-13-5 Enniatin B, a natural product isolated and purified from the Pencillium urticae with anticancer and antiangiogenic properties, can decrease Monocytes endocytosis ability and an increase of CD71.
CSN13532 Dihydroberberine 483-15-8 Dihydroberberine, a natural product isolated and purified from the tubers of Corydalis decumbens (Thunb.) Pers., has anti-tumor activity. Dihydroberberine improves in vivo efficacy in terms of counteracting increased adiposity, tissue triglyceride accumulation, and insulin resistance in high-fat-fed rodents, thus is potential therapeutic reagents for type 2 diabetes treatment.
CSN10762 Dehydrocorydaline 30045-16-0 Dehydrocorydaline, a natural product isolated and purified from the tubers of Corydalis ambigua, inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating BaxBcl-2, activating caspases as well as cleaving PARP.
CSN10751 Dauricine 524-17-4 Dauricine is a plant metabolite, chemically classified as a phenol, an aromatic ether, and an isoquinoline alkaloid.
CSN18820 Crotonoside 1818-71-9 Crotonoside is a naturally occurring active isomer of guanosine found in the seeds of Croton tiglium, which could reduce the blood pressure in rabbits and cats.
CSN16834 Cotinine 486-56-6 Cotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine, used as a biomarker for exposure to tobacco smoke.
CSN18353 Coptisine Chloride   6020-18-4 Coptisine Chloride is a naturally occuring cytotoxic alkaloid found in Chinese goldthread which shows cytotoxic effect on heptoma and leukemic cells and is reported to block cell cycle progression.
CSN10642 Cinchonine   118-10-5 Cinchonine is an alkaloid found in Cinchona officinalis, used to treat malaria.
CSN10608 Chelidonine 476-32-4 Chelidonine, a natural product isolated and purified from the herbs of Chelidonium majus L., efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKTPI3 kinase signalling pathways.
CSN12450 Cephalotaxine   24316-19-6 Cephalotaxine is a benzazepine alkaloid isolated from Cephalotaxus harringtonia with function of antiviral and antitumor.
CSN16581 Campathecin 7689-03-4 Camptothecin is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 M for breast cancer cell line MDA-MB-231.
CSN10121 Boldine 476-70-0 Boldine is an aporphine alkaloid, extracted from the leaves and bark of P. boldus, that possesses antioxidant and free-radical scavenging ability. Boldine may contain anti-inflammatory and antiproliferative properties, and the ability to cause cell cycle arrest at the G2M phase.
CSN10461 Bis(methylthio)gliotoxin 74149-38-5 Bis(methylthio)gliotoxin is an analog of gliotoxin known to inhibit PAF-induced platelet aggregation and collagen-aggregation, but has no activity with arachidonic or ADP induced aggregation.
CSN12859 Berberine HCl   633-65-8 Berberine HCl is an isoquinoline alkaloid isolated from the herb of Coptis chinensis Franch with anti-inflammatory and anti-diabetic effects.
CSN10246 Allantoin   97-59-6 Allantoin is a diureide of glyoxylic acid used as a skin conditioning agent.
CSN15002 Acetylcephalotaxine 24274-60-0 Acetylcephalotaxine is a natural product isolated and purified from the barks of Cephalotaxus fortunei with antitumor activity.
CSN13056 9-Nitrocamptothecin 86639-62-5 9-Nitrocamptothecin, a natural product, has a characterization of modified with transferrin for the treating of tumor.
CSN13080 9-Aminocamptothecin   91421-43-1 9-Aminocamptothecin, a natural product isolated and purified from the barks of Camptotheca acuminata Decne, is an active derivative of camptothecin, which belongs to the general group of chemotherapy drugs called topoisomerase inhibitors. 9-Aminocamptothecin is an inhibitor of Topo I.
CSN14162 7-Isopentenyloxy-gamma-Fagarine 23417-92-7 7-Isopentenyloxy-gamma-fagarine, a natural product isolated and purified from the fruits of Evodia lepta, has highly cytotoxicity against the MCF-7and Jurkat cell line.
CSN12784 5-Hydroxytryptophan   56-69-9 5-Hydroxytryptophan is a naturally occurring amino acid which acts as a chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.
CSN23630 3-(2-Hydroxyethyl)indole 526-55-6 3-(2-Hydroxyethyl)indole is an aromatic alcohol participate in many biological reactions.
CSN15293 19(S)-Hydroxyconopharyngine 16790-93-5 19(S)-Hydroxyconopharyngine can protect PC12 cells effectively against Abeta-induced toxicity.
CSN12999 Rocaglamide 84573-16-0
CSN15644 14-Norpseurotin A 1031727-34-0
CSN15643 Demethoxyfumitremorgin C 111768-16-2
CSN14545 5-Hydroxy-4-Methoxycanthin-6-One 18110-86-6
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