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ALDH

ALDH

Cat. No. Product Name CAS No. Information
CSN24614 Win 18446   1477-57-2 WIN 18446 is an inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2) with IC50 of 0.3 μM.
CSN19444 Prunetin 552-59-0 Prunetin can inhibit the aldehyde dehydrogenases in liver. It is a flavonoid compound isolated from the herbs of millettia dielsiana.
CSN10460 Disulfiram   97-77-8 Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram acts as an allosteric inhibitor of MERS-CoV PLpro but as a competitive (or mixed) inhibitor of SARS-CoV PLpro.
CSN16397 Daidzin   552-66-9 Daidzin can inhibit mitochondrial aldehyde dehydrogenase2 with IC50 of 80 nM and ALDH-I selectively (Ki20 nM). Daidzin is purified from the root of Pueraria lobata with effective anti-atherosclerotic activities.
CSN22782 CVT-10216 1005334-57-5 CVT 10216 is a potent and selective aldehyde dehydrogenase-2 ALDH2 inhibitor with IC50s of 29 and 1300 nM for ALDH2 and ALDH1 respectively
CSN25276 CM10 692269-09-3 CM10 is an ALDH1A inhibitor that depletes CD133+ cancer stem cells.
CSN18233 Alda-1 349438-38-6 Alda-1 is an ALDH2 agonist cell-permeable activator of both the wild-type ALDH21 and the asian E487K mutant ALDH22 forms of mitochondrial aldehyde dehydrogenase 2 mtALDH2
CSN23590 3,4-Dihydroxybenzeneacetic acid 102-32-9 34-Dihydroxyphenylacetic Acid is a metabolite of dopamine it can modulate the aldehyde dehydrogenase ALDH activity and protects the cells from the acetaldehyde-induced cytotoxicity in vitro
CSN22659 CM037 896795-60-1
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