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ADC Toxin

ADC Toxin

Cat. No. Product Name CAS No. Information
CSN26799 Py-MPB-amino-C3-PBD 2412924-07-1 Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Py-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity[1].
CSN16844 Methotrexate   59-05-2 Methotrexate, an antifolate compound, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH and can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.
CSN26800 Maytansinoid DM4 799840-96-3 Maytansinoid DM4 is a thiol-containing maytansine derivative with highly potent cytotoxicity. Maytansinoid DM4 can be used as a cytotoxic moiety of ADC[1][2].
CSN12607 Doxorubicin 23214-92-8 Doxorubicin is a topoisomerase II Top2 catalytic inhibitor also is a broad spectrum antibiotic used in the treatment of cancers with IC50 of 374 nM for Hela cells
CSN10750 Daunorubicin 20830-81-3 Daunorubicin, a topoisomerase II inhibitor, inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 M.
CSN26801 Aniline-MPB-amino-C3-PBD 2412923-79-4
CSN42097 Ansatrienin B 82189-04-6
CSN50538 AXC 715 313350-31-1
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