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ADC Toxin

ADC Toxin

Cat. No. Product Name CAS No. Information
CSN16844 Methotrexate   59-05-2 Methotrexate, an antifolate compound, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH and can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.
CSN12992 Maytansinol 57103-68-1 Maytansinol inhibits microtubule assembly and induces microtubule disassembly in vitro
CSN12607 Doxorubicin 23214-92-8 Doxorubicin is a topoisomerase II Top2 catalytic inhibitor also is a broad spectrum antibiotic used in the treatment of cancers with IC50 of 374 nM for Hela cells
CSN10750 Daunorubicin 20830-81-3 Daunorubicin, a topoisomerase II inhibitor, inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 M.
CSN16581 Campathecin 7689-03-4 Camptothecin is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 M for breast cancer cell line MDA-MB-231.
CSN10257 α-Amanitin 23109-05-9 alpha-Amanitin is a potent inhibitor of DNA-dependent RNA polymerase II
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