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AChR

AChR

Cat. No. Product Name CAS No. Information
CSN24539 Zamifenacin fumarate 127308-98-9 Zamifenacin fumarate is a selective M3 muscarinic receptor antagonist with pKi value of 8.52.
CSN27595 VU0238441   85511-68-8 VU0238441 is a potent agonist of muscarinic acetylcholine receptor M5 with EC50 of 2.1 μM.
CSN27586 VU0119498   79183-37-2 VU0119498 is a M1 muscarinic receptor agonist with EC50 of 3.1 μM, and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.
CSN24545 VU 10010 633283-39-3 VU 10010 is a selective allosteric potentiator of M4 acetylcholine receptor.
CSN24865 Raceanisodamine 17659-49-3 Raceanisodamine is the active ingredient of Chinese herbal extracts that has vasoactive activity used to treat acute disseminated intravascular coagulation in patients in bacteremic shock.
CSN17113 Promethazine HCl   58-33-3 Promethazine HCl is the effective antagonist of the H1 receptor and moderate antagonist of mACh receptor.
CSN25236 Pirmenol 68252-19-7 Pirmenol inhibited the muscarinic acetylcholine receptor-operated K+ current (I[K.ACh]) in atrial cells and on experimental atrial fibrillation in isolated guinea-pig hearts.
CSN24541 Perlapine 1977-11-3 Perlapine is a potent muscarinic DREADD agonist.
CSN24547 Oxotremorine sesquifumarate 17360-35-9 Oxotremorine sesquifumarate is a muscarinic agonist.
CSN24546 N,N,N-Trimethyl-4-(2-oxopyrrolidin-1-yl)but-2-yn-1-aminium iodide 3854-04-4 Oxotremorine M iodide is a potent and selective muscarinic acetylcholine receptor (mAChR) agonist. Oxotremorine M iodide potentiates NMDA receptors by muscarinic receptor dependent and independent mechanisms[1].
CSN24538 McN-A 343 55-45-8 McN-A 343 is a selective muscarinic M1 receptor agonist.
CSN24909 Sparteine 492-08-0 Inhibition of human CYP2D6 expressed in Escherichia coli JM109
CSN19397 Galanthamine 357-70-0 Galanthamine is a long-acting centrally active acetylcholinesterase AChE inhibitor IC50 410 nM and allosteric potentiator at neuronal nicotinic ACh receptors
CSN19398 Galanthamine Hydrobromide   1953-04-4 Galanthamine hydrobromide is a natural occuring AchE inhibitor with IC50 value of 410nM and allosteric potentiator at neuronal nAchRs used for the treatment of cognitive decline in mild to moderate Alzheimers disease and various other memory impairments
CSN24540 DAU 5884 HCl 131780-48-8 DAU 5884 HCl is a selective muscarinic M3 receptor antagonist.
CSN25424 Cyclopentolate HCl 5870-29-1 Cyclopentolate (DL-Cyclopentolate) hydrochloride is an Atropine-like muscarinic receptors antagonist with a pKB value of 7.8 (on the circular ciliary muscle). Cyclopentolate hydrochloride is an anti-muscarinic agent commonly used in the ophthalmologic practice.
CSN24531 Chlorisondamine diiodide 96750-66-2 Chlorisondamine diiodide is an exceptionally long lasting nicotinic antagonist with IC50 of ~ 1.6 mM.
CSN24542 Arecaidine propargyl ester tosylate 147202-94-6 Arecaidine propargyl ester tosylate is a potent muscarinic receptor agonist.
CSN24549 5-Methylfurmethiodide 1197-60-0 5-Methylfurmethiodide is a potent muscarinic agonist.
CSN24533 4-Acetyl-1,1-dimethylpiperazinium iodide 75667-84-4 4-Acetyl-1,1-dimethylpiperazinium iodide is a nAChR agonist with Ki of 29.9 nM at α4β2.
CSN24552 1-Acetyl-4-methylpiperazine hydrochloride 144205-68-5 1-Acetyl-4-methylpiperazine hydrochloride is a nAChR agonist.
CSN25275 (S)-PNU-282987 HCl 128311-08-0 (S)-PNU-282987 is the an absolute stereochemistry form of PNU-282987.
CSN24562 (S)-(+)-Dimethindene maleate 136152-65-3 (S)-(+)-Dimethindene maleate is a subtype-selective M2 muscarinic receptor antagonist with pKi of 7.78 and is also a H1 histamine receptor antagonist with pKi of 7.48.
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