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AChE

AChE

Cat. No. Product Name CAS No. Information
CSN12179 Valethamate Bromide 90-22-2 Valethamate bromide is generally used as an anticholinergic agent.
CSN12024 Tacrine HCl   1684-40-8 Tacrine HCl is a parasympathomimetic reversible cholinesterase inhibitor
CSN11851 Rivastigmine   123441-03-2 Rivastigmine is a acetylcholinesterase inhibitor with IC50 value of 5.5 M for cholinesterase, used for the treatment of mild to moderate Alzheimers disease and Parkinsons disease.
CSN11807 Pyridostigmine Bromide   101-26-8 Pyridostigmine is a reversible cholinesterase inhibitor to treat myasthenia gravis
CSN14156 Pseudopalmatine 19716-66-6 Pseudocolumbamine is a natural product isolated and purified from the herbs of Tinospora sinensis with antiplasmodial activity its also a AChE inhibitor with IC50 of 18 M
CSN17059 Pralidoxime Chloride   51-15-0 Pralidoxime chloride is an AChE reactivator used as an antidote to organophosphate pesticides and chemicals
CSN22325 (+)-Phenserine 116839-68-0 Posiphen is a selective cholinesterase noncompetitive inhibitor with an IC50 of 453 M
CSN20476 Pitofenone 54063-52-4 Pitofenone an AChE inhibitor with Ki values of 36 and 45 M for bovine erythrocyte and electric eel enzyme which shows anti-spasmodic activity in combination with Fenpiverinium and Diclofenac
CSN17727 Pipenzolate 13473-38-6 Pipenzolate is a muscarinic receptor antagonist preventing acetyl choline from binding to the receptors
CSN19869 Picfeltarraenin IA 97230-47-2 Picfeltarraenin IA a natural product isolated and purified from the herbs of Picria felterrae Lour is a stronger AChE inhibitor than the known AChE inhibitor Tacrine a potential PI3K and epidermal growth factor receptor EGFR inhibitor with anti-inflammatory activity and acts as an inhibitor on both the classical and alternative pathways of the complement system
CSN14039 N-p-trans-Coumaroyltyramine 36417-86-4 N-p-trans-Coumaroyltyramine a natural product isolated and purified from the herbs of Exochorda racemosa is an -glucosidase inhibitorKi 840 nM in yeast and an AChE inhibitor IC50 345 mgmL122 mM exhibits potent inhibition of cell proliferation platelet aggregation and shows antioxidant activity
CSN14738 N-Methylcalycinine 86537-66-8 N-Methylcalycinine a natural product isolated and purified from the root of Stephania epigaea exhibits potent AChE inhibitory activity
CSN15252 Lucidadiol 252351-95-4 Lucidadiol is a natural product isolated and purified from the herbs of fungus Ganoderma pfeifferi with inhibitory activity against acetylcholinesterase AChE with the percentage inhibition at 100 uM butyrylcholinesterase-inhibitory activity at concentrations up to 200 uM and antiviral activity against influenza virus type A and HSV type 1
CSN16680 Itopride HCl 122892-31-3 Itopride HCl is a D2 antagonist and an AChE inhibitor with an IC50 value of 204027 M It is a prokinetic benzamide derivative unlike domperidone
CSN19291 Huperzine A 102518-79-6 Huperzine A is a naturally occurring sesquiterpene alkaloid AChE inhibitor
CSN11139 Hederacoside C   14216-03-6 Hederacoside C is a naturally occuring saponin found in K pictus with anti-inflammatory activity It inhibited AChE with IC50 value of 313 M
CSN14086 Garcinone C 76996-27-5 Garcinone C a natural product isolated and purified from the fruits of Garcinia mangostana is the most potent inhibitor of AChE the most active compound against both of pathogenic MIC 100 gmL and non-pathogenic leptospira MIC 200 gmL and exhibits either significant or moderate cytotoxicity against MCF-7 A549 Hep-G2 and CNEhuman cancer cell lines in vitro
CSN19397 Galanthamine 357-70-0 Galanthamine is a long-acting centrally active acetylcholinesterase AChE inhibitor IC50 410 nM and allosteric potentiator at neuronal nicotinic ACh receptors
CSN12443 Galanthaminone 510-77-0 Galantamine is a competitive and reversible cholinesterase AChE inhibitor and is used for the treatment of mild to moderate Alzheimers disease and various other memory impairments
CSN10888 Edrophonium Chloride 116-38-1 Edrophonium chloride is a competitive AchE inhibitor which can prevent breakdown of the neurotransmitter acetylcholine
CSN16651 Donepezil   120014-06-4 Donepezil is a centrally acting reversible AchE inhibitor with IC50 of 812 nM and 116 nM for bAChE and hAChE respectively a medication used to treat Alzheimers disease
CSN21326 Dimetacrine 4757-55-5 Dimetacrine is a useful antidepressant which can be used for the treatment of various types of depression.
CSN10698 Corydaline 518-69-4 Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo
CSN10483 Bretylium Tosylate   61-75-6 Bretylium tosylate is an antiarrhythmic agent
CSN14035 beta-Amyrone 638-97-1 beta-Amyrone a natural product isolated and purified from the leaves of Cyclocarya paliums with snakevenom inactivating action exhibits moderate anti-acetylcholinesterase AChE activity
CSN19809 Acotiamide 185106-16-5 Acotiamide is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. It acts as an acetylcholinesterase inhibitor.
CSN23387 Acotiamide HCl   185104-11-4 Acotiamide HCl is the dihydrochloride form of acotiamide which is an inhibitor of AChE It also acts as a prokinetic drug through acetylcholinesterase inhibition and muscarinic receptor antagonism that is used for the treatment of functional dyspepsia
CSN22581 Acotiamide HCl 3H2O   773092-05-0 Acotiamide HCl 3H2O is AchE inhibitor which can increased Ach concentrations and lead to an improvement of gastric emptying and gastrointestinal motility and eventually to a reduction of dyspepsia symptoms.
CSN19329 3,4-Dicaffeoylquinic Acid   14534-61-3 34-Dicaffeoylquinic Acid is a polyphenol with diverse biological activities it inhibits acetylcholinesterase ACE and -glucosidase in a concentration-dependent manner shows cytotoxic to NCI-H23 lung adenocarcinoma cells as well as increases tumor necrosis factor-related apoptosis inducing ligand TRAIL mRNA reduces influenza H1N1 hemagglutinin HA mRNA and increases survival in a mouse model of influenza A infection
CSN16855 (±)-Huperazine A 120786-18-7 -Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs of Lycopodium serratum is a potent selective and reversible acetylcholinesterase AChE inhibitor and has been widely used in China for the treatment of Alzheimers disease AD
CSN14397 alpha-Viniferin 62218-13-7
CSN23810 Demecarium Bromide 56-94-0
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