Abbreviations

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Route

Intracerebroventricular

Intra-arterial

Intracerebral

Intradermal

ntramuscular

Intragastric

Intraperitoneal

Intravenous

Oral

Subcutaneous

Abbreviation

i.c.v.

i.a.

i.c.

i.d.

i.m.

i.g.

i.t.

i.v.

p.o.

s.c.

q.d.

b.i.d.

t.i.d.

Description

Into the ventricles of the brain

Into the lumen of an artery

Into the brain

Into the dermal layer of the skin

Into a skeletal muscle

Into the stomach

Into the spinal canal

Into a vein

By mouth

Under the skin

once a day

twice a day

three times a day

Abbreviation: Description
Abl: V-abl Abelson murine leukemia viral oncogene homolog 1
ALK: anaplastic lymphoma kinase
ATM: Ataxia telangiectasia mutated
B-Raf: B-Raf proto-oncogene serine/threonine-protein kinase (B-RAF), also known as V-raf murine sarcoma viral oncogene homolog B1
Bcl-2: B-cell lymphoma 2
bcr: breakpoint cluster region
Caspase: cysteine-aspartic proteases or cysteine-dependent aspartate-directed proteases
CCR5: co-receptors chemokine receptor 5
CDK: Cyclin-dependent kinase
CFTR potentiator: Cystic fibrosis transmembrane conductance regulator
CTSK: Cathepsin K, abbreviated CTSK
C-kit: CD117, also called KIT or C-kit receptor
c-Met: mesenchymal-epithelial transition factor
DNA-PK: DNA-dependent protein kinase
DPP-4: Dipeptidyl peptidase-4
EGFR: Epidermal growth factor receptor
Factor Xa: also known by the eponym Stuart-Prower factor or as prothrombin
FGFR: Fibroblast growth factor receptor
FLT-3: fms-like tyrosine kinase receptor-3
FTS: farnesyl thiosalicylic
GSK-3: Glycogen synthase kinase 3
HER2: Human Epidermal growth factor Receptor 2
Hedgehog: an intercellular signaling molecule called Hedgehog (Hh)
HDAC: Histone deacetylase
HIF: Hypoxia-inducible factor
HSP-70: heat-shock protein-70
HSP-90: heat-shock protein-90
IGF-1R: Insulin-like growth factor 1 receptor

Abbreviation: Description
JAK: Janus kinase
JNK: c-Jun N-terminal kinases
Ksp: Kinesin spindle protein
MAPK: Mitogen-activated Protein Kinase
MEK: MAPK/ERK kinase
mGlu2/3 receptors: metabotropic glutamate receptors
mTOR: Mammalian target of rapamycin
NF-kB: Nuclear factor Îº B
p38 MAPK: p38 Mitogen-activated Protein Kinase
p53: protein 53 or tumor protein 53
PARP: Poly (ADP-ribose) polymerase
PDGFR: platelet-derived growth factor receptor
PDK-1: phosphoinositide-dependent kinase-1
Rho: Ï factor
PI3K: Phosphatidylinositol 3-kinases
PKC: protein kinase C
PLK: Polo-like kinase
Ras: renin-angiotensin system
RNA Polymerase I: RNAP or RNApol
S1PR1: sphingosine-1-phosphate receptor 1ï¼also known as S1P1 or EDG1
(endothelial differentiation gene 1)
sPLA2: Secreted phospholipases A2
Src: Rous sarcoma oncogene cellular homolog
Stat: Signal Transducers and Activator of Transcription
Survivin: also called baculoviral inhibitor of apoptosis repeat-containin 5 orBIRC5
TGF-beta: Transforming growth factor
TNF-alpha: Tumor necrosis factors
VEGFR-PDGFR: Vascular Endothelial Growth Factor Receptor -platelet derived growth factor receptor
Wee1: Small cell protein, a mitotic inhibitor kinase
Wnt: a combination of Wg (wingless) and Int