||5-Methyl-2-Furaldehyde is a naturally occuring volatile compound used as potential age marker for Madeira wine.
||Homovanillic Acid is a dopamine metabolite occurring in human biofluids, also barks of Ilex rotunda Thunb.
||Auraptene is a natural product isolated and purified from the peel of Poncirus trifoliata with anti-tumor and anti-oxidant activity. Auraptene-mediate
||Daucosterol is a naturally occuring phytosterol-like compound, role as a plant metabolite. It is a steroid saponin, a beta-D-glucoside and a monosacch
||7-Amino-4-methylcoumarin is a natural product isolated and purified from an endophytic Xylaria fungal species and exhibited strong antibacterial and a
||Methyleugenol is a naturally occuring phenylpropene found in a number of plants. It is important to insect behavior and pollination.
||Entinostat strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM.
||Perillartine is a naturally occuring sweetener found most abundantly in the annual herb perilla.
||Phytic Acid Sodium
||Phytic Acid Sodium
||Pterostilbene is a natural dietary compound with antioxidant, antiproliferative, antihyperglycemic and antidiabetic effect, and is also an apoptosis i
||Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
||Stevioside, a natural product isolated and purified from the leaves of Stevia rebaudiana, is a safe natural sweetener, has no allergic reactions, suit
||Vorinostat is an HDAC1/3 inhibitor with IC50 of ~10 nM.
||Galangin functions as an antagonist of the aryl hydrocarbon receptor and also inhibits CYP1A1 (IC50 1 M). It belongs to flavonoids and can be extract
||Triacetylresveratrol is a prodrug of resveratrol with multiple targets including sirt, COX, IKK and LOX, etc..
||Selumetinib is a potent, highly selective MEK1 inhibitor with IC50 of 14 nM, also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to
||Tetrahydrocurcumin, a natural product isolated and purified from the rhizomes of Curcuma longa L., is one of the major metabolites of Curcumin. It is
||GSK2126458 is a highly selective and potent inhibitor of PI3K with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM for p110α/β/δ/γ, mTORC1/
||Docetaxel, an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules.
||Diosgenin, a natural product isolated and purified from the rhizomes of Dioscorea zingiberensis C.H.Wright, is an important natural source of steroida
||Panobinostat is a broad-spectrum HDAC inhibitor with IC50 of 5 nM in a cell-free assay.
||AZD8055 is an ATP-competitive mTOR inhibitor with IC50 of 0.8 nM with excellent selectivity (～1,000-fold) against PI3K isoforms and ATM/DNA-PK.
||Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel exerts it
||7-Epitaxol is a natural product isolated and purified from the barks of Taxus chinensis (Pilger) Rehd. which is the major derivative of taxol found in
||Romidepsin is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.
||Phlorizin significantly inhibits oxidative DNA damage, it is a natural product isolated and purified from the herbs of Prunus armeniaca L..
||Alpelisib is a potent and selective PI3Kα inhibitor with IC50 of 5 nM, liitle or no effect on PI3Kβ/γ/δ.
||ACY-1215 is a selective HDAC6 inhibitor with IC50 of 5 nM, being > 10-fold selective for HDAC6 than HDAC1/2/3 (IC50 = 58, 48, and 51 nM) with slight a
||AZD2014 is an mTOR inhibitor with IC50 of 2.8 nM and is highly selective against multiple PI3K isoforms (α/β/γ/δ).
||Cobimetinib is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, showing more than 100-fold selectively for MEK1 over MEK2 and showed
||Palbociclib isethionate is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional
||Pracinostat is a potent pan-HDAC inhibitor with IC50 of 40-140 nM with exception for HDAC6 and has no activity against the class III isoenzyme SIRT I.
||Narirutin is a flavanone-7-O-glycoside with antiproliferative, anti-depressant and anti-inflammatory properties. It can be isolated from the young fru
||L-Chicoric acid, a natural product isolated and purified from the herbs of Echinacea purpurea, is an inhibitor of human immunodeficiency virus type 1
||Anethole trithione is a drug used in the treatment of dry mouth, being studied in the treatment of cancer.
||Solamargine is a naturally-occuring glycoalkaloid isolated from plants of the Solanaceae family which has been used in trials studying the treatment o
||LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50s of 1.5 nM and 0.9 nM for GSK-3α and GSK-3β respectively.
||IPI-549 is a selective phosphoinositide-3-kinase (PI3K)-γ inhibitor with IC50 of 16 nM as an immuno-oncology clinical candidate.
||Rhein is a lipophilic anthraquinone extensively found in medicinal herbs, and has many pharmacological effects, including epatoprotective, nephroprote
||Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
||6-Maleimidohexanoic Acid N-Hydroxysuccinimide Ester
||6-Maleimidohexanoic Acid N-Hydroxysuccinimide Ester is used for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
||Fmoc-Val-Cit-PAB-OH is a linker for ADC through cleaveage by catepsin B only present in lysosome at Val-Cit site, thus making ACD payload be released
||Val-Cit-PAB-OH is a linker for ADC through cleaveage by catepsin B only present in lysosome at Val-Cit site, thus making ACD payload be released only
||Deoxynojirimycin HCl, a natural product isolated and purified from the root barks of Morus alba L., shows inhibitory activity against α-glucosidases,
||Plantamajoside, a natural product isolated and purified from the herb of Plantago depressa Willd., has anti-hepatotoxic, anti-inflammatory, antinocice
||Crocin, a natural product with anti-inflammatory, antihyperlipidemic, antidepressant and anti-apoptotic effects, can ameliorate CCl4-induced liver inj
||Myrislignan is a natural product with antifungal properties its isolated and purified from the seeds of Myristica fragrans Houtt
||Diosbulbin B, a natural product isolated and purified from the roots of Dioscorea bulbifera, has potential anti-tumor effects which may be related to
||Urolithin A is a metabolite of ellagitannin with antiproliferative and antioxidant properties. It can cross the blood brain barrier, and may have neur
||3,4-Dimethoxybenzoic acid is a natural product isolated and purified from the fruits of Phyllanthus emblica L..